Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (07): 1532-1535.DOI: 10.6023/cjoc201304029 Previous Articles     Next Articles



王广银a, 吕绪良a, 翁枭迪a, 汤雪峰b, 荣先辉b   

  1. a 解放军理工大学电磁环境效应与光电工程重点实验室 南京 210007;
    b 解放军理工大学科研部 南京 210007
  • 收稿日期:2013-04-19 修回日期:2013-05-13 发布日期:2013-05-15
  • 通讯作者: 吕绪良

Synthesis of Polysubstituted Electron-Deficient Cyclobutane via Michael Addition and Oxidative Cyclization

Wang Guangyina, Lv Xulianga, Weng Xiaodia, Tang Xuefengb, Rong Xianhuib   

  1. a Key Laboratory of Science and Technology on Electro-magnetic Environmental Effects and Electro-optical Engineering, PLA University of Science and Technology, Nanjing 210007;
    b Department of Scientific Research, PLA University of Science and Technology, Nanjing 210007
  • Received:2013-04-19 Revised:2013-05-13 Published:2013-05-15

An efficient synthetic method to polysubstituted electron-deficient cyclobutane from simple starting materials was developed. The key reactions were a Michael addition and an iodine(III)-mediated oxidative cyclization. The structure of product was confirmed by its single-crystal diffraction analysis. A tentative pathway for the oxidative cyclization was proposed.

Key words: cyclobutane, Michael addition, oxidative cyclization