Chin. J. Org. Chem. ›› 2014, Vol. 34 ›› Issue (6): 1110-1117.DOI: 10.6023/cjoc201401042 Previous Articles     Next Articles



赵志刚, 王晓红, 石治川, 程玉宇   

  1. 西南民族大学化学与环境保护工程学院 成都 610041
  • 收稿日期:2014-01-25 修回日期:2014-03-10 发布日期:2014-04-15
  • 通讯作者: 赵志刚
  • 基金资助:

    四川省科技支撑计划基金(No. 2012SZ0160)和国家外专局基金(No. 2013-32)资助项目.

Synthesis of Molecular Tweezers Derived from Chenodeoxycholic Acid through Click Reaction and Their Recogniton Properties

Zhao Zhigang, Wang Xiaohong, Shi Zhichuan, Cheng Yuyu   

  1. College of Chemistry and Environmental Protection Engineering, Southwest University for Nationalities, Chengdu 610041
  • Received:2014-01-25 Revised:2014-03-10 Published:2014-04-15
  • Supported by:

    Project supported by the Science and Technology Department of Sichuan Province (No. 2012SZ0160) and the National Foreign Expert Bureau (No. 2013-32).

Twelve novel chenodeoxycholic acid-based molecular tweezer metal receptors containing 1,2,3-triazole moieties have been designed and synthesized using click chemistry method. The target compounds were characterized by 1H NMR, IR, MS spectra and elemental analysis. Their binding properties were examined by UV-Vis spectra titration. The results indicate that these molecular tweezers showed high selectivity and affinity for Hg2+ ion.

Key words: cation recognition, molecular tweezer, click chemistry, 1,2,3-triazole, chenodeoxycholic acid