Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (12): 2552-2558.DOI: 10.6023/cjoc201506024 Previous Articles     Next Articles



段希焱a, 段希斌b, 杨坤a, 王志成a, 张璐a, 佟悦a, 刘浩哲a, 杜珂a, 唐榕泽a   

  1. a 河南科技大学化工与制药学院 洛阳 471023;
    b 郑州大学附属郑州中心医院 郑州 450007
  • 收稿日期:2015-06-18 修回日期:2015-07-24 发布日期:2015-08-26
  • 通讯作者: 段希焱
  • 基金资助:

    河南科技大学博士科研启动项目(No. 4008-13480042).

PhI(OAc)2/I2-Mediated Oxidative Homocoupling of N-Alkoxyamides: An Approach to Esters

Duan Xiyana, Duan Xibinb, Yang Kuna, Wang Zhichenga, Zhang Luaa, Tong Yuea, Liu Haozhea, Du Kea, Tang Rongzea   

  1. a School of Chemical Engineering & Pharmaceutics, Henan University of Science and Technology, Luoyang 471023;
    b Zhengzhou Certral Hospital Affiliated to Zhengzhou University, Zhengzhou 450007
  • Received:2015-06-18 Revised:2015-07-24 Published:2015-08-26
  • Supported by:

    Project supported by the Students Research Training Program of Henan University of Science and Technology (No. 4008-13480042).

A variety of substituted N-alkoxyamides derivatives were found to be converted to the corresponding esters mediated by PhI(OAc)2/I2. This novel strategy allows for an efficient synthesis of esters and is highlighted by appealing features such as readily available of the starting material, mild reaction condition, wide substrate scope and transition-metal-free characteristics.

Key words: hypervalent iodine, N-alkoxyamides, ester, oxidative coupling