Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (7): 1596-1601.DOI: 10.6023/cjoc201601019 Previous Articles     Next Articles



周鹏, 邱会华, 潘泓成, 施继成, 周建敏   

  1. 广东石油化工学院化学工程学院 茂名 525000
  • 收稿日期:2016-01-15 修回日期:2016-03-16 发布日期:2016-04-05
  • 通讯作者: 周鹏
  • 基金资助:


Researches on the α-Aminoxylation between α-Azoleketones and 2,2,6,6-Tetramethylpiperidine-1-oxyl with Cu/O2

Zhou Peng, Qiu Huihua, Pan Hongcheng, Shi Jicheng, Zhou Jianmin   

  1. School of Chemical engineering, Guangdong University of Petrochemical Technology, Maoming, 525000
  • Received:2016-01-15 Revised:2016-03-16 Published:2016-04-05
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21272037), the Natural Science Foundation of Guangdong Province (No. S2013040014944) and the Guangdong University of Petrochemical Technology (No. 2015DCA037).

The α-aminoxylation between α-azoleketones and 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) was studied in this paper. Taking Cu(II) salts as catalyst and air as oxidant, a number of alkoxyamines have been synthesized via α-aminoxylation between α-azoleketones and TEMPO in good yields at room temperature. This strategy is highlighted by appealing features such as mild reaction condition, inexpensive catalyst, green oxidant and good yield.

Key words: Cu catalyzed, dioxygen, α-azoleketone, 2,2,6,6-tetramethylpiperidine-1-oxyl, α-aminoxylation