Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (9): 2121-2129.DOI: 10.6023/cjoc201603002 Previous Articles     Next Articles



田文艳a,b, 徐松a,b,c, 梁中卫a,b, 孙德立a,b, 张荣华a,b   

  1. a 同济大学化学系 上海 200092;
    b 上海市化学评估与可持续发展重点实验室 上海 200092;
    c 嘉兴学院化学与制药工程学院 嘉兴 31400
  • 收稿日期:2016-03-03 修回日期:2016-04-29 发布日期:2016-05-19
  • 通讯作者: 张荣华
  • 基金资助:


Synthesis of Oxindoles by Eosin Y Catalyzed under Visible Light

Tian Wenyana,b, Xu Songa,b,c, Liang Zhongweia,b, Sun Delia,b, Zhang Ronghuaa,b   

  1. a Department of Chemistry, Tongji University, Shanghai 200092;
    b Shanghai Key Laboratory of Chemical Assessment and Sustainability, Shanghai 200092;
    c College of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing 31400
  • Received:2016-03-03 Revised:2016-04-29 Published:2016-05-19
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No.20972113/B020502).

A novel visible-light-introduced reaction for the construction of oxindole derivatives via tandem radical cyclization of N-aryl acrylamides with diethyl bromomalonate has been developed. The reaction has been achieved in high yield under mild conditions by using Eosin Y as photocatalyst, which is cheap, easy to handle and environmentally friendly. It might provide a promising protocol for the synthesis of oxindole derivatives.

Key words: eosin Y, photoredox catalysis, oxindoles, radical cyclization