Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (5): 1273-1277.DOI: 10.6023/cjoc201612015 Previous Articles     Next Articles



俞峥炜, 李林奕, 沈增明   

  1. 上海交通大学化学化工学院 上海 200240
  • 收稿日期:2016-12-06 修回日期:2017-01-05 发布日期:2017-01-17
  • 通讯作者: 沈增明
  • 基金资助:


Cu-Catalyzed Cyanation of Aryl Iodides with Acetonitrile as Cyano Source

Yu Zhengwei, Li Linyi, Shen Zengming   

  1. School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240
  • Received:2016-12-06 Revised:2017-01-05 Published:2017-01-17
  • Contact: 10.6023/cjoc201612015
  • Supported by:

    Project supported by the National Natural Sciences Foundation of China (Nos. 21272001, 21672144) and the Shanghai Education Committee (No. 13ZZ014).

A Cu-catalyzed protocol for the cyanation of aryl iodides by using acetonitrile as the “CN” source has been developed, in which the Cu(cat.)/2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO)/Si system shows good reactivity and generality. Both electron-rich and electron-deficient functional groups can be tolerated in this system.

Key words: Cu catalyst, cyanation, acetonitrile, aryl iodide, 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO)