Recent Progress in the Synthesis of N2-Substituted 1, 2, 3-Triazoles

doi:10.6023/cjoc201710018

Chin. J. Org. Chem. ›› 2018, Vol. 38 ›› Issue (5): 1052-1064.DOI: 10.6023/cjoc201710018 Previous Articles Next Articles

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N²-取代1,2,3-三唑的合成研究进展

朱莉莉^a, 张辉^a, 王春杰^a, 陈自立^b

a 周口师范学院化学化工学院周口 466001;
b 中国人民大学化学系北京 100872

收稿日期:2017-12-16 修回日期:2017-12-20 发布日期:2018-01-10
通讯作者: 朱莉莉,E-mail:lily77cq@163.com;陈自立,E-mail:zilichen@ruc.edu.cn E-mail:lily77cq@163.com;zilichen@ruc.edu.cn
基金资助:
国家自然科学基金（No.21472237）、河南省科技计划项目（No.162300410197）、周口师范学院科研创新基金（No.ZKNUA201701）和周口师范学院科研启动基金（No.ZKNUB2013001）资助项目.

Recent Progress in the Synthesis of N²-Substituted 1, 2, 3-Triazoles

Zhu Lili^a, Zhang Hui^a, Wang Chunjie^a, Chen Zili^b

a School of Chemistry and Chemical Engneering, Zhoukou Normal University, Zhoukou 466001;
b Department of Chemistry, Renmin University of China, Beijing 100872

Received:2017-12-16 Revised:2017-12-20 Published:2018-01-10
Contact: 10.6023/cjoc201710018 E-mail:lily77cq@163.com;zilichen@ruc.edu.cn
Supported by:
Project supported by the National Natural Science Foundation of China (No. 21472237), the Science and Technology Research Program of Henan Province (No. 162300410197), the Scientific Research Innovation Foundation of Zhoukou Normal University (No. ZKNUA201701) and the Doctoral Scientific Research Foundation of Zhoukou Normal University (No. ZKNUB2013001).

N-Substituted 1, 2, 3-triazole is an important structural unit in organic chemistry, and has widely utilized in organic synthesis, medicinal chemistry and material science. The chemistry of N¹-substituted 1, 2, 3-triazoles has attracted much attention from organic chemists, while the synthesis and application of their N²-isomers have been far less explored. The recent progress on the research field of N²-alkyl, allyl, propargyl, vinyl, aryl substituted 1, 2, 3-triazoles since year 2000 is summarized, including some research of our group. The content is classified by different synthetic methods, such as selective functionalization of 1, 2, 3-triazoles and oxidative cyclization of bisarylhydrazones or azobenzenes.

Key words: 1, 2, 3-triazole, selective N²-fuctionalization, alkylation, allylation, propargylation, vinylation, arylation, cyclization

Cite this article

Zhu Lili, Zhang Hui, Wang Chunjie, Chen Zili. Recent Progress in the Synthesis of N²-Substituted 1, 2, 3-Triazoles[J]. Chin. J. Org. Chem., 2018, 38(5): 1052-1064.

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N²-取代1,2,3-三唑的合成研究进展

Recent Progress in the Synthesis of N²-Substituted 1, 2, 3-Triazoles

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N2-取代1,2,3-三唑的合成研究进展