Chin. J. Org. Chem. ›› 2018, Vol. 38 ›› Issue (5): 1052-1064.DOI: 10.6023/cjoc201710018 Previous Articles     Next Articles



朱莉莉a, 张辉a, 王春杰a, 陈自立b   

  1. a 周口师范学院化学化工学院 周口 466001;
    b 中国人民大学化学系 北京 100872
  • 收稿日期:2017-12-16 修回日期:2017-12-20 发布日期:2018-01-10
  • 通讯作者: 朱莉莉,;陈自立,;
  • 基金资助:


Recent Progress in the Synthesis of N2-Substituted 1, 2, 3-Triazoles

Zhu Lilia, Zhang Huia, Wang Chunjiea, Chen Zilib   

  1. a School of Chemistry and Chemical Engneering, Zhoukou Normal University, Zhoukou 466001;
    b Department of Chemistry, Renmin University of China, Beijing 100872
  • Received:2017-12-16 Revised:2017-12-20 Published:2018-01-10
  • Contact: 10.6023/cjoc201710018;
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21472237), the Science and Technology Research Program of Henan Province (No. 162300410197), the Scientific Research Innovation Foundation of Zhoukou Normal University (No. ZKNUA201701) and the Doctoral Scientific Research Foundation of Zhoukou Normal University (No. ZKNUB2013001).

N-Substituted 1, 2, 3-triazole is an important structural unit in organic chemistry, and has widely utilized in organic synthesis, medicinal chemistry and material science. The chemistry of N1-substituted 1, 2, 3-triazoles has attracted much attention from organic chemists, while the synthesis and application of their N2-isomers have been far less explored. The recent progress on the research field of N2-alkyl, allyl, propargyl, vinyl, aryl substituted 1, 2, 3-triazoles since year 2000 is summarized, including some research of our group. The content is classified by different synthetic methods, such as selective functionalization of 1, 2, 3-triazoles and oxidative cyclization of bisarylhydrazones or azobenzenes.

Key words: 1, 2, 3-triazole, selective N2-fuctionalization, alkylation, allylation, propargylation, vinylation, arylation, cyclization