Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (9): 2549-2559.DOI: 10.6023/cjoc201902003 Previous Articles     Next Articles



万洪维, 于健, 杨寿山, 杜广芬, 何林   

  1. 石河子大学化学化工学院 石河子 832000
  • 收稿日期:2019-02-08 修回日期:2019-04-21 发布日期:2019-04-26
  • 通讯作者: 杜广芬
  • 基金资助:


Formal[2+1] Annulation of Thiazoles and Stable Sulfur Ylide

Wan Hongwei, Yu Jian, Yang Shoushan, Du Guangfen, He Lin   

  1. School of Chemistry and Chemical Engineering, Shihezi University, Shihezi 832000
  • Received:2019-02-08 Revised:2019-04-21 Published:2019-04-26
  • Contact: 10.6023/cjoc201902003
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21662029) and the Young Scientists Foundation of Shihezi University (Nos. RCZX201546, 2015ZRKXJQ05).

Thiazolones underwent formal[2+1] annulation with stable sulfur ylide to construct cyclopropane-fused spiro-thiazolone derivatives in 30%~99% yields with good diastereoselectivity.

Key words: thiazolones, sulfur ylide, annulation, spiro-cyclopropane