Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (11): 3559-3595.DOI: 10.6023/cjoc202006072 Previous Articles     Next Articles

C,N-环状偶氮次甲基亚胺参与的反应研究进展

华庭碧a,b, 阳青青a,b, 肖文精c   

  1. a 三峡大学 天然产物研究与利用湖北省重点实验室 湖北宜昌 443002;
    b 三峡大学材料与化工学院 无机非金属晶态与能源转换材料重点实验室 湖北宜昌 443002;
    c 华中师范大学化学学院 农药与化学生物学教育部重点实验室 武汉 430079
  • 收稿日期:2020-06-30 修回日期:2020-09-04 发布日期:2020-09-16
  • 通讯作者: 阳青青, 肖文精 E-mail:qingqing_yang@ctgu.edu.cn;wxiao@mail.ccnu.edu.cn
  • 基金资助:
    国家自然科学基金(No.21702121)、三峡大学天然产物研究与利用湖北重点实验室开放基金(No.NPRD-2018010)、三峡大学学位论文培优基金和高等学校学科创新引智计划(111计划,No.D20015)资助项目.

Recent Developments of Reactions with C,N-Cyclic Azomethine Imines

Hua Tingbia,b, Yang Qingqinga,b, Xiao Wengjingc   

  1. a Hubei Key Laboratory of Natural Products Research and Development, China Three Gorges University, Yichang, Hubei 443002;
    b Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials, College of Materials and Chemical Engineering, China Three Gorges University, Yichang, hubei 443002;
    c Key Laboratory of Pesticide&Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079
  • Received:2020-06-30 Revised:2020-09-04 Published:2020-09-16
  • Supported by:
    Project supported by the National Natural Science Foundation of China (No. 21702121), the Open Fund from Hubei Key Laboratory of Natural Products Research and Development (China Three Gorges University) (No. NPRD-2018010), the Research Fund for Excellent Dissertation of China Three Gorges University and the Programme of Introducing Talents of Discipline to Universities (111 Project, No. D20015).

Among various 1,3-dipoles of cyclic azomethine imines, C,N-cyclic azomethine imines are the most widely used reagents in the construction of diverse tetrahydroisoquinoline derivatives. The developments of reactions with C,N-cyclic azomethine imines including [3+2], [3+3], [3+4], [5+1], [3+1] cycloaddition reactions and miscellaneous reactions are summarized. The properties of reactions, reaction processes and synthetic applications are discussed. Finally, the prospects of the reaction with this reagent are also proposed.

Key words: 1,3-dipole, azomethine imine, C,N-cyclic azomethine imine, cycloaddition reaction, isoquinoline derivative