Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (9): 3459-3481.DOI: 10.6023/cjoc202103032 Previous Articles     Next Articles



刘想*(), 李文, 庄灿展, 曹华   

  1. 广东药科大学医药化工学院 广东省化妆品工程技术研究中心 广东中山 528458
  • 收稿日期:2021-03-19 修回日期:2021-04-04 发布日期:2021-06-07
  • 通讯作者: 刘想
  • 基金资助:
    国家自然科学基金(22001045); 广东省创新强校项目(2019KQNCX061); 省市共建重点学科建设专项资助项目.

Application of Photochemical/Electrochemical Synthesis in C—H Functionalization of Quinoxalin-2(1H)-one

Xiang Liu(), Wen Li, Canzhan Zhuang, Hua Cao   

  1. Guangdong Cosmetics Engineering & Technology Research Center, School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan, Guangdong 528458
  • Received:2021-03-19 Revised:2021-04-04 Published:2021-06-07
  • Contact: Xiang Liu
  • Supported by:
    National Natural Science Foundation of China(22001045); Innovation and Strong School Project of Guangdong Pharmaceutcal University(2019KQNCX061); Special Funds of Key Disciplines Construction from Guangdong and Zhongshan Cooperating.

Quinoxalin-2(1H)-ones are a kind of important nitrogen-containing heterocyclic compounds, which have strong biological activity and chemical properties, and play an important role in synthesis chemistry, functional materials, drugs and so on. In recent years, the construction of 3-functionalized quinoxalin-2(1H)-one by C—H functionalization has attracted the attention of many scholars and made important progress. Among them, green chemistry oriented photocatalysis and electrochemical synthesis are becoming powerful tools for C—H functionalization of quinoxaline-2(1H)-one. In view of the great influence of photochemistry in synthetic chemistry, the research status of C—H functionalization of quinoxaline- 2(1H)-one in visible light catalysis and electrochemical synthesis is summarized, hoping to promote the further development of green synthesis strategy in the functionalization of nitrogen-containing heterocycles.

Key words: quinoxalin-2(1H)-one, visible-light, electrochemistry, C—H functionalization