Studies on the acylthiosemicarbazides and the related heterocyclic compounds XII: Synthesis of 1-(α-phenylcyanoacetylamino)-3-aroylthiourea and 3-(α-phenylcyanomethyl)-4-4-aroyl-1,2,4-triazole-5-thiol derivatives

Chin. J. Org. Chem. ›› 1989, Vol. 9 ›› Issue (2): 150-155. Previous Articles Next Articles

酰氨基硫脲及其相关杂环衍生物的研究 XII: 1-(α-苯基氰乙酰胺基)-3-芳酰基硫脲及3-(α-苯基氰甲基)-4-芳酰基-1,2,4-三唑-5-硫酚衍生物的合成

张自义;陈立民;冯小明;曾福礼

兰州大学化学系;西南师范大学化学系;兰州大学生物系

发布日期:1989-04-25

Studies on the acylthiosemicarbazides and the related heterocyclic compounds XII: Synthesis of 1-(α-phenylcyanoacetylamino)-3-aroylthiourea and 3-(α-phenylcyanomethyl)-4-4-aroyl-1,2,4-triazole-5-thiol derivatives

ZHANG ZIYI;CHEN LIMIN;FENG XIAOMING;ZENG FULI

Published:1989-04-25

Abstract

Refluxing PhCH(CN)CONHNH2 with RCONCS [R = (un)substituted Ph, a-naphthyl, 2-thienyl, PhCH:CH] in MeCN gave 65.3-97.6% PhCH(CN)CONHNHC(S)NHCOR (I), cyclization of which with aqueous NaOH gave 61.2-96.4% triazolethiols III. I (R = 2-O2NC6H4) showed strong promoting activity on the growth of plumule of wheat at 10-3-10-1 ppm.

Key words: AMIDES, INFRARED SPECTROPHOTOMETRY, ELEMENTAL ANALYSIS, MASS SPECTROGRAPHY, NMR SPECTROMETRY, THIOUREAS, BENZENE P, CARBOXYLIC ACID ESTER, HYDRAZIDE, HETEROCYCLIC COMPOUNDS, PYRRODIAZOLE P, THIOPHENOLS, CYANOACETIC ACID P, CYANOACETIC ACID P, ISOTHIOCYANIC ACID

CLC Number:

O621

Cite this article

ZHANG ZIYI;CHEN LIMIN;FENG XIAOMING;ZENG FULI. Studies on the acylthiosemicarbazides and the related heterocyclic compounds XII: Synthesis of 1-(α-phenylcyanoacetylamino)-3-aroylthiourea and 3-(α-phenylcyanomethyl)-4-4-aroyl-1,2,4-triazole-5-thiol derivatives[J]. Chin. J. Org. Chem., 1989, 9(2): 150-155.

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酰氨基硫脲及其相关杂环衍生物的研究 XII: 1-(α-苯基氰乙酰胺基)-3-芳酰基硫脲及3-(α-苯基氰甲基)-4-芳酰基-1,2,4-三唑-5-硫酚衍生物的合成

Studies on the acylthiosemicarbazides and the related heterocyclic compounds XII: Synthesis of 1-(α-phenylcyanoacetylamino)-3-aroylthiourea and 3-(α-phenylcyanomethyl)-4-4-aroyl-1,2,4-triazole-5-thiol derivatives

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