Chin. J. Org. Chem. ›› 1993, Vol. 13 ›› Issue (4): 431-433. Previous Articles     Next Articles

Original Articles

Δ^4-3, 6-二酮甾体结构单元合成的改进

苏向东;李振肃   

  1. 北京医科大学药学院.北京(100083)
  • 发布日期:1993-08-25

An improved synthesis of Δ^4-3, 6-dione steroidal moiety

Su Xiangdong;Li Zhensu   

  1. Beijing Med Univ, Coll Pharmaceut Sci.Beijing(100083)
  • Published:1993-08-25

Oxidation of cholesterol (1a) and 16, 17α -epoxy-3-hydroxy-Δ^5- pregnene-20-one (1b) to the corresponding Δ^4-3, 6-diones has been achived in high yield by one-step process, using high nolar ratio of Pyridinium Chlorochromate (PCC) buffered with sodium acetate.

Key words: STEROL, CHOLESTEROL, OXIDATION

CLC Number: