Chin. J. Org. Chem. ›› 2001, Vol. 21 ›› Issue (1): 8-15. Previous Articles     Next Articles

O-磷酸酰化多肽及其类似物的化学合成

赵刚;李艳梅;陈忠周;赵玉芬   

  1. 清华大学化学系.北京(100084);生命有机磷化学教育部重点实验室
  • 发布日期:2001-01-25

The chemical synthesis of O-phosphopeptide and its analogue

Zhao Gang;Li Yanmei;Chen Zhongzhou;Zhao Yufen   

  1. Tsing Hua Univ, Dept Chem.Beijing(100084)
  • Published:2001-01-25

O-Phosphopeptide and its analogue play an important role in the study and elucidation of the regulation mechanism of protein reversible phosphorylation in life activities. The synthesis of O- phosphopeptide and the related researches are international hot field of life sciences. This paper reviews the modern chemical approaches for the synthesis of O-phosphopeptide and its analogues.

Key words: POLYPEPTIDE, PROTEIN, PHOSPHORYL COMPOUNDS, PHOSPHORYLATION, ENZYME REACTION, SOLIDPHASE SYNTHESIS

CLC Number: