Synthesis and Herbicidal Activities of 1-Pyrazol-5'-ylcar-bonyl-4-arylsemicarbazide

Chin. J. Org. Chem. ›› 2005, Vol. 25 ›› Issue (11): 1454-1458. Previous Articles Next Articles

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1-吡唑酰基-4-芳基氨基脲类化合物的合成及除草活性

谭成侠*^,1，沈德隆¹，翁建全¹，欧晓明²

(¹浙江工业大学化学工程与材料学院杭州 310032)
(²国家南方农药创制中心湖南基地生测部长沙 410007)

收稿日期:2005-03-27 修回日期:2005-05-17 发布日期:2005-10-30
通讯作者: 谭成侠

Synthesis and Herbicidal Activities of 1-Pyrazol-5'-ylcar-bonyl-4-arylsemicarbazide

TAN Cheng-Xia*^,1,SHEN De-Long¹,WENG Jian-Quan¹,OU Xiao-Ming²

(¹College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310014)
(²Bioassay Department, Hunan Branch of National Southern Pesticide Research Centre, Changsha 410007)

Received:2005-03-27 Revised:2005-05-17 Published:2005-10-30
Contact: TAN Cheng-Xia

Abstract

In order to find new semicarbazide lead compounds, 1-pyrazol-5'-ylcarbonyl-4-substituted phen-ylsemibazides were synthesized from 4-bromo-3-ethyl-1-methyl-5-hydrazinocarbonylpyrazole and substi-tuted phenyl isocyanate. The structures of all new compounds were confirmed by ¹H NMR, IR, MS spectra and elemental analysis. The results of biological tests indicated that, at the concentration of 225 mg/m², 1-(4-bromo-3-ethyl-1-methyl-pyrazol-5'-ylcarbonyl)-4-(2,4-dimethylphenyl)semicarbazide (4k) showed inhibitory activities (100%) against Abutilon theophrasti, Chenopodium album and Amaranthus spinosus.

Key words: semicarbazide, herbicidal activity, pyrazole

Cite this article

TAN Cheng-Xia*^,1,SHEN De-Long,WENG Jian-Quan,OU Xiao-Ming². Synthesis and Herbicidal Activities of 1-Pyrazol-5'-ylcar-bonyl-4-arylsemicarbazide[J]. Chin. J. Org. Chem., 2005, 25(11): 1454-1458.

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1-吡唑酰基-4-芳基氨基脲类化合物的合成及除草活性

Synthesis and Herbicidal Activities of 1-Pyrazol-5'-ylcar-bonyl-4-arylsemicarbazide

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