Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (08): 1031-1033. Previous Articles     Next Articles

Reports

3-(3-叔丁氧基)丁二酰亚胺基单环β-内酰胺衍生物的合成

张萍a,王萍a,b 李媛*,a   

  1. (a河北师范大学化学与材料科学学院 石家庄 050016)
    (b河北化工医药职业技术学院化工系 石家庄 050012)
  • 收稿日期:2006-06-20 修回日期:1900-01-01 发布日期:2007-07-30
  • 通讯作者: 李媛*

Synthesis of New 3-(3-t-Butoxyl)succinimidyl Monocyclic β-Lactams

ZHANG Pinga, WANG Pinga,b, LI Yuan*,a   

  1. (a College of Chemistry, Hebei Normal University, Shijiazhuang 050016)
    (b Department of Chemistry and Enginering, Hebei Chemical and Pharmacutical Vocational Technology College,
    Shijiazhuang 050012)
  • Received:2006-06-20 Revised:1900-01-01 Published:2007-07-30
  • Contact: LI Yuan*

3-(3-t-Butoxyl)succinimidyl acetyl chloride was obtained by a series of reactions starting from malic acid. 3-(3-t-Butoxyl)succinimidyl acetyl chloride reacted with Schiff bases 1a1h to yield 8 new 3-(3-t-butoxyl)succinimidyl monocyclic β-lactam derivatives 2a2h. The structures of the new compounds were confirmed by IR, 1H NMR, MS spectra and elemental analysis.

Key words: Schiff base, monocyclic β-lactam, 3-(3-t-butoxyl)succinimide acetyl chloride