Chin. J. Org. Chem. ›› 2011, Vol. 31 ›› Issue (12): 2173-2177. Previous Articles     Next Articles

Notes

一锅法Kumada偶联反应合成烷基吡啶化合物

刘涛平,谢俊杰,李彬,蔡良珍*,陶晓春*   

  1. (华东理工大学化学与分子工程学院 上海 200237)
  • 收稿日期:2011-07-03 修回日期:2011-09-15 发布日期:2011-09-30
  • 通讯作者: 陶晓春 E-mail:xctao@ecust.edu.cn

Synthesis of Alkylpyridines via One-Pot Kumada Reaction

LIU Tao-Ping, XIE Jun-Jie, LI Bin, CAI Liang-Zhen, TAO Xiao-Chun   

  1. (School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237)
  • Received:2011-07-03 Revised:2011-09-15 Published:2011-09-30

A series of methyl-, allyl-, benzyl-substituted pyridines were prepared in moderate yield, using bromopyridines as starting material and a simple structure nickel complex (Py4NiCl2) as catalyst by one-pot Kumada reaction.

Key words: Kumada reaction, bromopyridine, nickel-catalyzed, one-pot