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化学学报
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化学学报 ›› 1981, Vol. 39 ›› Issue (3): 203-208. 上一篇    下一篇

论文

核磁位移试剂测定16α-羟基-16β-甲基-⊿4,17(20)-孕甾二烯-3-酮的构型——用假接触模型解释诱导位移

王绮文, 陈朝环, 陈毓群   

  1. 中国科学院上海有机化学研究所
  • 投稿日期:1979-04-04 发布日期:2013-06-03

LSR STUDY OF THE CONFIGURATION OF THE 16α-HYDROXYL-16β-METHYL-Δ4, 17(20)-PREGNADIEN-3-ONE——INTERPRETATION OF PSEUDO-CONTACT MODEL FOR LIS

WANG QI-WEN, CHEN ZHAO-HUAN, CHEN YU-QUN   

  1. Shanghai Institute of Organic Chemistry, Academia Sinica
  • Received:1979-04-04 Published:2013-06-03

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本文报道了应用镧系位移试剂研究两个孕甾二烯酮异构体(1和2)的17(20)位双键的构型,以Eu(dpm)3为试剂,对假接触位移方程θi=K·(3cos2θi-1)/ri3进行回归分析.对1用结构E时,求得R=0.0144,对2用结构Z时,R=0.107.根据回归线分离了OH及C=0分别对C4-H的贡献之后,求得Eu(dpm)3对OH及C=O的络合比大致为10:1.

LSR study of the configuration of 17(20) double bond of two pregnadienone isomers is reported. Eu (dpm)3 was used as shift reagent and a small compuler performed the regression analysis for equation Δi=K·(3cos2θi-1)/ri3.