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化学学报
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化学学报 ›› 1988, Vol. 46 ›› Issue (12): 1201-1206. 上一篇    下一篇

研究论文

箭根薯属(Tacca)苦味成分的研究-箭根酮内酯A和B的结构

陈仲良;王保德;陈民勤   

  1. 中国科学院上海药物研究所;复旦大学化学系
  • 发布日期:1988-12-15

Bitter principles from tacca plants structures of taccalonolide A and B

CHEN ZHONGLIANG;WANG BAODE;CHEN MINQIN   

  • Published:1988-12-15

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从裂果薯中分得三种新型甾族苦味成分, 通过光谱解析, 推定箭根酮内酯A和B的结构前者对肿瘤细胞有抑制作用, 并对鼠疟原虫有杀灭作用.

关键词: 内酯, 分子结构, 碳13核磁共振谱法, 甾族化合物, 质子磁共振谱法, 酮 P, 薯科

Tacca plantaginea is a herbaceous plant found in the South of China, its rhizome has long been used for analgesic, anti-inflammatory, and wound healing. Steroidal bitter principles, taccalonolide A (I, R = Ac) and B (I, R = H) were identified by spectroscopic methods. I inhibited growth of the tumor cell line P-388 and Plasmodium berghei.

Key words: LACTONES, MOLECULAR STRUCTURE, C13 NMR SPECTROMETRY, STEROIDS, PROTON MAGNETIC RESONANCE SPECTROMETRY, KETONE P, TACCACEAE

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