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化学学报
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化学学报 ›› 1998, Vol. 56 ›› Issue (9): 833-839.    下一篇

研究论文

硒和箬叶多糖对细菌生长代谢作用热化学特征研究

颜承农;刘义;陈春英;屈松生;徐辉碧   

  1. 武汉大学化学系.武汉(430072);华中理工大学化学系.武汉;荆州师范 高等专科学校
  • 发布日期:1998-09-15

Thermochemical characteristics of the action of Na~2SeO~3 and ruoye polysaccharides on bacteria

Yan Chengnong;Liu Yi;Chen Chunying;Qu Songsheng;Xu Huibi   

  1. Wuhan Univ, Dept Chem.Wuhan(430072);Central China Univ of Polytech, Dept of Chem.Wuhan
  • Published:1998-09-15

PDF

459

被引次数

25

用微量热法研究了Na~2SeO~3和箬叶多糖对大肠杆菌和产气肠杆菌作用的热功率输出曲线,得到了大肠杆菌和产气肠杆菌在不同条件下的生长速率常数k等参数。结果表明:Na~2SeO~3在低浓度下对大肠杆菌生长有促进作用,在高浓度时对两种细菌均有很强的抑制作用,而箬叶多糖对大肠杆菌和产气肠杆菌生长代谢未表现出抑制作用。这为揭示硒的生物效应、进行药理学和毒理学等的研究、寻找高效低毒的新药提供了可靠的信息。

关键词: 箬叶多糖, 多糖, 硒, 硒酸盐, 钠盐, 微量热法, 热动力学, 细菌, 生长速率, 肠道微生物

The thermokinetic characteristics of the actions of Na~2SeO~3 and four kinds of ruoye polysaccharides on Escharichia coli and Aerobacter aerogenes have been studied by means of microcalorimetry. It was found that low concentration of Na~2SeO~3 and polysaccharides had promoting action on the growth of cells, and high concentration of Na~2SeO~3 had inhibitory action on the two bacteria, and ruoye polysaccharides did not show inhibitory action. For different drugs, the mechanism of action may be different. It was provided a lot of information on the bioaffect of selenium.

Key words: POLYSACCHARIDE, SELENIUM, SELENATE, SODIUM SALT, MICROCALORIMETRIC METHOD, THERMODYNAMICS, BACTERIA, GROWTH RATE, ENTERIC MICROORGANISM, ESCHERICHIA COLI

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