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化学学报
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化学学报 ›› 2008, Vol. 66 ›› Issue (2): 223-228. 上一篇    下一篇

研究论文

化学发光物质9-[2',6'-二甲基-4'-(琥珀酰亚胺氧羰基)苯氧羰基]-10-甲基吖啶-单甲基-磺酸盐的合成

尹东光1,2，贺佑丰2，刘一兵2，沈德存2，韩世泉2，罗志福2，焦正1，吴明红*,1   

  1. (1上海大学环境与化学工程学院 上海 200444)
    (2中国原子能科学研究院同位素研究所 北京 102413)
  • 投稿日期:2007-01-31 修回日期:2007-07-10 发布日期:2008-01-28
  • 通讯作者: 吴明红

Synthesis of a Chemiluminescent Reagent of 9-[2',6'-Dimethyl-4'- (succinimidoxycarbonyl)phenoxycarbonyl]-10-methylacridinium monomethyl Sulfate

YIN Dong-Guang1,2 HE You-Feng2 LIU Yi-Bing2 SHEN De-Cun2 HAN Shi-Quan2 LUO Zhi-Fu2 JIAO Zheng1 WU Ming-Hong*,1   

  1. (1 College of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444)
    (2 Department of Isotope, China Institute of Atomic Energy, Beijing 102413)
  • Received:2007-01-31 Revised:2007-07-10 Published:2008-01-28
  • Contact: WU Ming-Hong

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923

被引次数

11

报道了一种化学发光物质吖啶酯衍生物9-[2',6'-二甲基-4'-(琥珀酰亚胺氧羰基)苯氧羰基]-10-甲基吖啶-单甲基-磺酸盐(DMAE•NHS)的合成, 合成共经历7个步骤, 每步合成的产物经IR, 1H NMR, MS和元素分析表征, 结果表明合成产物为所期望的化合物. 该合成产物显示为一种非常理想的化学发光物质.

关键词: 吖啶酯, 9-[2',6'-二甲基-4'-(琥珀酰亚胺氧羰基)苯氧羰基]-10-甲基吖啶-单甲基-磺酸盐(DMAE•, NHS), 化学发光, 合成

Synthesis of an acridinium salt, 9-[2',6'-dimethyl-4'-(succinimidoxycarbonyl)phenoxycarbonyl]-10-methylacridinium monomethyl sulfate, was investigated. The synthesis involved seven steps and all of the intermediate compounds and the final product were identified by IR, 1H NMR, MS and elemental analysis, respectively. Results of our farther study show that the synthesized compound as a chemiluminescent reagent owns more advantages.

Key words: acridinium slat, 9-[2',6'-dimethyl-4'-(succinimidoxycarbonyl)phenoxycarbonyl]-10-methyl- acridinium monomethyl sulfate (DMAE•, NHS), chemiluminescence, synthes