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化学学报
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化学学报 ›› 1976, Vol. 34 ›› Issue (1): 39-44. 上一篇    下一篇

论文

山莨菪碱的化学研究

  

  1. 1. 中国医学科学院药物研究所植物化学研究室;
    2. 青海省医学科学研究所
  • 投稿日期:1975-08-04 发布日期:2013-06-03

CHEMICAL STUDIES ON ANISODAMINE

DEPARTMENT OF PHYTOCHEMISTRY, INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES INSTITUTE OF MEDICAL SCIENCES, CHINGHAI   

  • Received:1975-08-04 Published:2013-06-03

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848

被引次数

10

从唐古特山莨菪[Anisodus tanduticus(Maxim)Pascher]植物中分离出来的山莨菪碱具有胆碱能神经阻滞作用,可用于治疗急性微循环障碍性疾病,经化学研究证明山莨菪碱即为已知的6S羟i基天仙子胺.

Anisodamine(trade name "654") is an alkaloid isolated from the medicinal plant Anisocwus tanguticus.(Maxim) Pascher.On the basis of pharmacological and clinical studies,anisodamine as a new anticholinergio drug,may be used for the treatment of acute microoironlatory disturbances.Based on chemioal studies,anisodamine was identified as 6 -hydrogyhyosoyamine and the stereoconfiguration of the hydroxy-group is 6S.It is one of the major constituents in Anisodus tangutieus(Maxim) Pascher.