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化学学报
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化学学报 ›› 1956, Vol. 22 ›› Issue (6): 460-466. 上一篇    下一篇

论文

3-烃硫基-4-甲基-N-(二烃氨基乙基)苯胺类化合物的制备

丁振闿, 张其楷   

  1. 医学科学院
  • 投稿日期:1956-06-25 发布日期:2013-06-03

PREPARATION OF 3-ALKYLMERCAPTO-4-METHYL-N-(DIALKYL-AMINOETHYL)ANILINES

TING ZHEN-KAI, CHANG CHI-CHIEK   

  1. Institute of Medical Sciences
  • Received:1956-06-25 Published:2013-06-03

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本文叙述从4-甲基乙醯苯胺为原料,经过五个步骤合成了3-烃硫基-4-甲基-N-(二烃氨基乙基)苯胺(Ⅱ)类化合物十种。并制备了中间产物3-烃硫基-4-甲基乙醯苯胺与3-烃硫基-4-甲基苯胺各四种。

Ten new compounds of 3-alkylmercapto-4-methyl-N-(dialkylaminoethyl) anilines (Ⅱ),structurally derived from Miracil D, have been prepared for the purpose of testing their chemo-therapeutic activity toward Schistosomiasis Jaqonica. Several unknown intermediates of 3-alkylmercapto-4-methylanilines and their acetyl compounds are reported.