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化学学报
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化学学报 ›› 2014, Vol. 72 ›› Issue (5): 552-556.DOI: 10.6023/A14030155 上一篇    下一篇

研究通讯

Pd/MgO：一种基于芳香羧酸脱羧与卤代芳烃的交叉偶联反应体系的可循环的多相催化剂

李召好b, 陈静a, 苏伟平a, 洪茂椿a   

  1. a 中国科学院煤制乙二醇及相关技术重点实验室 结构化学国家重点实验室 中国科学院福建物质结构研究所 福州 350002;
    b 洛阳师范学院化学化工学院 471022
  • 投稿日期:2014-03-11 发布日期:2014-04-13
  • 通讯作者: 苏伟平 E-mail:wpsu@fjirsm.ac.cn
  • 基金资助:

    项目受973（Nos. 2011CB932404，2011CBA00501）、国家自然科学基金（No. 21103192）和中科院重点项目资助.

Pd/MgO：A Recyclable, Ligand-free Heterogeneous Catalyst for Decarboxylative Cross-Coupling of Arene Carboxylic Acids with Aryl Halides

Li Zhaohaob, Chen Jinga, Su Weipinga, Hong Maochuna   

  1. a Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002;
    b College of Chemistry and Chemical Engineering, Luoyang Normal University, Luoyang 471022
  • Received:2014-03-11 Published:2014-04-13
  • Supported by:

    Project supported by the 973 Program (Nos. 2011CB932404, 2011CBA00501), the National Natural Science Foundation of China (No. 21103192) and the Key Project from Chinese Academy of Sciences.

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补充材料

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发展了钯多相催化剂Pd/MgO （0.5 mol% Pd）参与的芳基羧酸脱羧与卤代芳烃的偶联反应体系. 在与溴代芳烃甚至氯代芳烃的偶联反应中，缺电子和富电子的芳基羧酸均能进行脱羧，并以高收率得到目标产物. 该体系采用的负载型钯多相催化剂制备方法简单易行，可多次循环使用，能便捷地应用于脱羧偶联的有机合成反应.

关键词: 钯, 脱羧, 芳基羧酸, 偶联, 多相催化

Decarboxylative coupling of arene carboxylic acids with aryl halides is achieved by using a ligand-free Pd/MgO (0.5 mol% Pd) heterogeneous catalyst system. Both electron-rich and electron-deficient arene carboxylic acids can be used as aryl sources to couple a variety of aryl bromides, even aryl chlorides in moderate-to-excellent yields. The establishment of heterogeneous catalysis for the decarboxylative cross-coupling along with the reusability of the heterogeneous catalyst should facilitate the practical application of this transformation in organic synthesis.

Key words: palladium, decarboxylation, carboxylic acid, cross-coupling, heterogeneous catalysis