Study on the alkylation of α-carbon of β-ketosulfone catalyzed by quaternary ammonium base resin

Acta Chimica Sinica ›› 1990, Vol. 48 ›› Issue (6): 622-626. Previous Articles

Original Articles

季铵碱树脂催化的β-酮砜的α-碳烷基化反应研究

任启生;黄文强;陆宇;尹耀荣;何炳林

南开大学高分子化学研究所

发布日期:1990-06-15

Study on the alkylation of α-carbon of β-ketosulfone catalyzed by quaternary ammonium base resin

REN QISHENG;HUANG WENQIANG;LU YU;YIN YAORONG;HE BINGLIN

Published:1990-06-15

Abstract

The alkylation of a-methylene of PhSO2CH2COPh (I) with alkyl halides catalyzed by quaternary ammonium base resin in 50% aqueous sodium hydroxide solution was investigated. In the presence of triphase catalyst, the alkylation products of I depended closely on the reactivity of alkyl halides and reaction temperature The a-carbon and O-dialkylation product was found when aprotic solvent HMPA was present at 50癈. No alkylation product but the decomposition product of I was obtained at 100?

Key words: SULFONE, METHYLENE, INFRARED SPECTROPHOTOMETRY, BENZENE, NMR SPECTROMETRY, ALKYLATION, ACETOPHENONE P, PHASE TRANSFER CATALYST, SULFONYL GROUP, RESIN

CLC Number:

O621
O643

Cite this article

REN QISHENG;HUANG WENQIANG;LU YU;YIN YAORONG;HE BINGLIN. Study on the alkylation of α-carbon of β-ketosulfone catalyzed by quaternary ammonium base resin[J]. Acta Chimica Sinica, 1990, 48(6): 622-626.

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季铵碱树脂催化的β-酮砜的α-碳烷基化反应研究

Study on the alkylation of α-carbon of β-ketosulfone catalyzed by quaternary ammonium base resin

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