Acta Chimica Sinica ›› 1994, Vol. 52 ›› Issue (8): 813-816. Previous Articles     Next Articles

Original Articles

大环二萜圆盘肉芝内酯的分子构型研究

苏镜娱;钟永利;娄瑰霞;李小清;曾陇梅;黄幼青;胡盛志   

  1. 中山大学化学系;厦门大学化学系
  • 发布日期:1994-08-15

Studies on the stereochemistry of (-)-sartrochine

SU JINGYU;ZHONG YONGLI;LOU GUIXIA;LI XIAOQING;ZENG LONGMEI;HUANG YOUQING;HU SHENGZHI   

  • Published:1994-08-15

A new macrocyclic diterpenoid lactone, (-)-sartrochine (I), was isolated from the soft coral Sarcophyton trocheliophorum, which showed cytotoxic activity against S180 cells and antibiotic effect on Streptococcus. The mol. structure and the relative stereochem. were determine by spectroscopic data and x-ray diffraction anal. The absolute configuration was assigned by CD method.

Key words: CRYSTAL STRUCTURE, X-RAY DIFFRACTION ANALYSIS, CIRCULAR DICHROISM, BIOLOGICAL TESTS, SOFT CORAL, ANTINEOPLASTIC ACTIVITY

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