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Acta Chimica Sinica ›› 2007, Vol. 65 ›› Issue (15): 1511-1514. Previous Articles     Next Articles

Original Articles

3-(1-亚胺基氟烷基)-1H-喹啉-2-酮类化合物的合成研究

杨先金*,1,2, 袁文娇1, 刘金涛*,2   

  1. (1华东理工大学先进材料与制备实验室 精细化工研究所 上海 200237)
    (2中国科学院上海有机化学研究所有机氟化学重点实验室 上海 200032)
  • 投稿日期:2006-10-30 修回日期:2007-02-25 发布日期:2007-08-14
  • 通讯作者: 刘金涛

Study on the Syntheses of 3-(1-Iminofluoroalkyl)-1H-quinolin-2-one Derivatives

YANG Xian-Jin*,1,2; YUAN Wen-Jiao1; LIU Jin-Tao*,2   

  1. (1 Laboratory of Advanced Materials and Institute of Fine Chemicals, East China University of Sci-ence and Technology, Shanghai 200237)
    (2 Key Laboratory of Organofluorine Chemis-try, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032)
  • Received:2006-10-30 Revised:2007-02-25 Published:2007-08-14
  • Contact: LIU Jin-Tao

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2-Fluoroalkyl acetic acids were converted to their corresponding carbonyl chlorides, which was then reacted with o-amino benzaldehyde and ammonia gas to give 3-(1-iminofluoroalkyl)-1H-qunolin-2- ones in moderate yields.

Key words: 2-fluoroalkylacetic acid, o-amino benzaldehyde, 3-(1-iminofluoroalkyl)-1H-quinolin-2-one, synthesis