Chiral Resolution of Curcumol Epoxy Derivatives by Ionic Liquid [BMIm]BF4

Acta Chimica Sinica ›› 2010, Vol. 68 ›› Issue (24): 2619-2621. Previous Articles

Note

离子液体[BMIm]BF₄对莪术醇手性环氧异构体的拆分

郭平¹^{,2，刘剑敏²，李校堃²，杨树林*^{,1，姚其正*^,3}}

(¹南京理工大学化工学院南京 210094)
(²温州医学院药学院温州 325035)
(³中国药科大学药学院南京 210009)

投稿日期:2010-06-24 修回日期:2010-08-16 发布日期:2010-08-30
通讯作者: 姚其正 E-mail:qz_yao@yahoo.com.cn

Chiral Resolution of Curcumol Epoxy Derivatives by Ionic Liquid [BMIm]BF₄

Guo Ping¹^{,2 Liu Jianmin² Li Xiaokun² Yang Shulin*^{,1 Yao Qizheng*^,3}}

(¹Institute of Chemical Technology, Nanjing University of Science and Technology, Nanjing 210094)
(²School of Pharmacy, Wenzhou Medical College, Wenzhou 325035)
(³School of Pharmacy, China Pharmaceutical University, Nanjing 210009)

Received:2010-06-24 Revised:2010-08-16 Published:2010-08-30

Abstract

The isomers of 10,14-epoxy curcumol derivatives were separated by the ionic liquid [BMIm]BF₄, in which there is a difference in the solubility of the complexes formed with the isomers and [BMIm]BF₄. The yield 22% of (10R)-10,14-epoxy curcumol (E1) with 99% ee and the yield 49% of (10S)-10,14-epoxy curcumol (E2) with 92% ee were obtained respectively in the resolution. The ionic liquid could be recovered easily and used again with the same separation effect.

Key words: ionic liquid, chiral resolution, curcumol, 10,14-epoxycurcumol

Cite this article

GUO Ping, LIU Jian-Min, LI Xiao-Kun, YANG Shu-Lin, YAO Qi-Zheng. Chiral Resolution of Curcumol Epoxy Derivatives by Ionic Liquid [BMIm]BF₄[J]. Acta Chimica Sinica, 2010, 68(24): 2619-2621.

Export EndNote|Reference Manager|ProCite|BibTeX|RefWorks

[1]	Shaojuan Zeng, Xueqi Sun, Yinge Bai, Lu Bai, Shuang Zheng, Xiangping Zhang, Suojiang Zhang. Research Progress of CO₂ Capture and Separation by Functionalized Ionic Liquids and Materials^★ [J]. Acta Chimica Sinica, 2023, 81(6): 627-645.
[2]	Wen Liu, Yujie Wang, Huiqin Yang, Chengjie Li, Na Wu, Yang Yan. The Preparation of Carbon Nanotubes/Reduced Graphene Oxide Current Collector by Non-covalent Induction of Ionic Liquid for Sodium Metal Anode [J]. Acta Chimica Sinica, 2023, 81(10): 1379-1386.
[3]	Xiaoqian Li, Jing Zhang, Fangfang Su, Dechao Wang, Dongdong Yao, Yaping Zheng. Construction and Application of Porous Ionic Liquids [J]. Acta Chimica Sinica, 2022, 80(6): 848-860.
[4]	Wenjun Wu, Yuting Li, Xi Feng, Wenxing Ding. Perovskite Dual-function Passivator: Room Temperature Ionic Liquid Obtained from Mechanochemical Preparation [J]. Acta Chimica Sinica, 2022, 80(11): 1469-1475.
[5]	He-Nan Wang, An-Ge Zhang, Zhong Zhang, Hong-Rui Tian, Qian Yue, Xue Zhao, Ying Lu, Shu-Xia Liu. Synthesis and Properties of a Series of Pure Inorganic Ionic Liquids Based on Rare Earth Cations and Polyoxometalates [J]. Acta Chimica Sinica, 2021, 79(7): 920-924.
[6]	Yumiao Lu, Wei Chen, Yanlei Wang, Feng Huo, Yihui Dong, Li Wei, Hongyan He. Research Progress on the Preparation and Properties of Two Dimensional Structure of Ionic Liquids [J]. Acta Chimica Sinica, 2021, 79(4): 443-458.
[7]	Wang Yinhang, Li Wei, Luo Sha, Liu Shouxin, Ma Chunhui, Li Jian. Research Advances on the Applications of Immobilized Ionic Liquids Functional Materials [J]. Acta Chim. Sinica, 2018, 76(2): 85-94.
[8]	Qiu Huayu, Zhao Jingwen, Zhou Xinhong, Cui Guanglei. Research Progress of Ionic Liquid-Inorganic Particle Hybrid Electrolytes in Secondary Batteries [J]. Acta Chimica Sinica, 2018, 76(10): 749-756.
[9]	Zhang Chuan, Zhang Lujia, Zhang Yang, Huang He, Hu Yi. Study on the Stability and Enzymatic Property Improvement of Porcine Pancreas Lipase Modified by Ionic Liquids Using Molecular Simulation [J]. Acta Chim. Sinica, 2016, 74(1): 74-80.
[10]	He Xuexia, Liu Fucai, Zeng Qingsheng, Liu Zheng. Electric-double-layer Transistors Based on Two Dimensional Materials [J]. Acta Chim. Sinica, 2015, 73(9): 924-935.
[11]	Leng Minghao, Chen Shimou, Zhang Junling, Lang Haiyan, Kang Yanhong, Zhang Suojiang. Effects of Organic Additives Containing Carbonyl Group on Electrodeposition of Al from AlCl₃-[Emim]Cl Ionic Liquid [J]. Acta Chim. Sinica, 2015, 73(5): 403-408.
[12]	Qian Wenjing, Yuan Chao, Guo Jiangna, Yan Feng. A Review of Poly(Ionic Liquid)s Based Functional Materials [J]. Acta Chim. Sinica, 2015, 73(4): 310-315.
[13]	Liu Mengying, Che Jianing, Wu Weihong, Lu Yunxiang, Peng Changjun, Liu Honglai, Lu Hao, Yang Qiang, Wang Hualin. Extraction of Copper from Aqueous Solution with Functional Ionic Liquids: Experiment and Theoretical Calculation [J]. Acta Chim. Sinica, 2015, 73(2): 116-125.
[14]	Yang Cuilian, Huangfu Lixia, Su Hang, Guo Kaihua. Determination of pH Value and Acid-base Property of Ionic Liquid Aqueous Solutions [J]. Acta Chimica Sinica, 2014, 72(4): 495-501.
[15]	Yu Fengli, Tang Huibao, Liu Chunyu, Xie Congxia, Yu Shitao. Oxidative Desulfurization of Model Diesel with O₂ Catalyzed by Oxidative-thermoregulated Bifunctional Ionic Liquids [J]. Acta Chimica Sinica, 2014, 72(11): 1152-1156.

离子液体[BMIm]BF₄对莪术醇手性环氧异构体的拆分

Chiral Resolution of Curcumol Epoxy Derivatives by Ionic Liquid [BMIm]BF₄

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments

离子液体[BMIm]BF4对莪术醇手性环氧异构体的拆分