Synthesis and Anti-diabetic Activity of Bis(α-furancarboxylato) oxovanadium (IV)

Acta Chimica Sinica ›› 2002, Vol. 60 ›› Issue (5): 892-896. Previous Articles Next Articles

Original Articles

双（α－呋喃甲酸）氧钒的合成和抗糖尿病活性研究

谢明进;刘伟平;李玲;陈植和

昆明贵金属研究所,昆明(650221);昆明医学院天然药物理重点实验室,昆明 (650031)

发布日期:2002-05-15

Synthesis and Anti-diabetic Activity of Bis(α-furancarboxylato) oxovanadium (IV)

Xie Mingjin;Liu Weiping;Li Ling;Chen Zhihe

Kunming Institute of Precious Metals,Kunming(650221);Kunming Medical College,Kunming(650031)

Published:2002-05-15

Abstract

Bis(α-furancarboxylato) oxovanadium (IV) was designed and synthesized. Its chemical structure was determined by using elemental analysis, IR, UV, MS and ~1H NMR spectra. This complex was submitted to the test of preliminary toxicity and anti-diabetic activity in mice. The results show that bis(α-furancarboxylato)-oxovanadium (IV) is safe and can significantly lower the glucose level in blood of mice, exhibiting potential application in treating diabetes.

Key words: OXYGEN COMPLEX, VANADIUM COMPLEX, FURANCARBOXYLIC ACID P, ELEMENTAL ANALYSIS, IR, UV

CLC Number:

O611.662

Cite this article

Xie Mingjin;Liu Weiping;Li Ling;Chen Zhihe. Synthesis and Anti-diabetic Activity of Bis(α-furancarboxylato) oxovanadium (IV)[J]. Acta Chimica Sinica, 2002, 60(5): 892-896.

Export EndNote|Reference Manager|ProCite|BibTeX|RefWorks

[1]	Jianqiang Chen, Gangguo Zhu, Jie Wu. Recent Advances in Nickel-Catalyzed Ring Opening Cross-Coupling of Aziridines [J]. Acta Chimica Sinica, 2024, 82(2): 190-212.
[2]	Weiyang Gao, Weichao Deng, Yang Gao, Renxiao Liang, Yixia Jia. Intermolecular Enantioselective Dearomative Oxidative Heck Reaction of Indoles [J]. Acta Chimica Sinica, 2024, 82(1): 1-4.
[3]	Chen Li, Xiao Si, Jinbo Li, Yan Zhang. Chemical Modification and Delivery System of Small Interfering RNA Drugs^★ [J]. Acta Chimica Sinica, 2023, 81(9): 1240-1254.
[4]	Kai Zhang, Xiaojun Wu. Room-Temperature Ferromagnetism in Two-Dimensional Janus Titanium Chalcogenides^★ [J]. Acta Chimica Sinica, 2023, 81(9): 1142-1147.
[5]	Yi Wan, Jianghua He, Yuetao Zhang. Research Progress in Precision Polymerization of Polar Olefin Monomers by Lewis Pairs^★ [J]. Acta Chimica Sinica, 2023, 81(9): 1215-1230.
[6]	Peng Tao, Xiaokang Zheng, Guoliang Wang, Xinghao Sheng, He Jiang, Wentao Li, Jibiao Jin, Sui-Hung Wong, Yanqin Miao, Hua Wang, Wai-Yeung Wong. Novel Bipolar Orange Emissive Iridium(III) Complexes: Design, Synthesis, and Electroluminescence^★ [J]. Acta Chimica Sinica, 2023, 81(8): 891-897.
[7]	Yujie Yang, Yuxiu Gong, Tianhang Gu, Wei-xian Zhang. Progress and Environmental Research Applications of Cryo-Electron Microscopy^★ [J]. Acta Chimica Sinica, 2023, 81(8): 990-1001.
[8]	Xinhong Cai, Jianzhong Chen, Wanbin Zhang. Development of Construction of Chiral C—X Bonds through Nickel Catalyzed Asymmetric Hydrogenation^★ [J]. Acta Chimica Sinica, 2023, 81(6): 646-656.
[9]	Yinfeng Wang, Meng Li, Chuanfeng Chen. Chiral Triptycene-Based Red Thermally Activated Delayed Fluorescence Polymers and Their Organic Light-Emitting Diodes^★ [J]. Acta Chimica Sinica, 2023, 81(6): 588-594.
[10]	Wang Rui-Xiang, Zhao Qing-Ru, Gu Qing, You Shu-Li. Gold/Iridium Catalyzed Alkynylamide Cyclization/Asymmetric Allylic Benzylation Cascade Reaction^★ [J]. Acta Chimica Sinica, 2023, 81(5): 431-434.
[11]	Jie Yang, Lin Ling, Yuxue Li, Long Lu. Density Functional Theory Study on Thermal Decomposition Mechanisms of Ammonium Perchlorate [J]. Acta Chimica Sinica, 2023, 81(4): 328-337.
[12]	Junliang Zhou, Zhenxin Zhao, Tingyi Wu, Xiaomin Wang. Efficient Catalytic Conversion of Polysulfides in Multifunctional FeP/Carbon Cloth Interlayer for High Capacity and Stability of Lithium-sulfur Batteries [J]. Acta Chimica Sinica, 2023, 81(4): 351-358.
[13]	Yeqiang Han, Bingfeng Shi. Palladium(II)-Catalyzed Enantioselective Functionalization of C(sp³)—H Bonds^★ [J]. Acta Chimica Sinica, 2023, 81(11): 1522-1540.
[14]	Yang Gao, Xuexin Zhang, Jinsheng Yu, Jian Zhou. Recent Advances in Catalytic Enantioselective Synthesis of α-Chiral Tertiary Azides^★ [J]. Acta Chimica Sinica, 2023, 81(11): 1590-1608.
[15]	Guan-Wen Yang, Guang-Peng Wu. Modular Bifunctional Organoboron-ammonium/phosphonium Catalysts: Design and Catalytic Performance^★ [J]. Acta Chimica Sinica, 2023, 81(11): 1551-1565.

双（α－呋喃甲酸）氧钒的合成和抗糖尿病活性研究

Synthesis and Anti-diabetic Activity of Bis(α-furancarboxylato) oxovanadium (IV)

PDF

Knowledge

Cited

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments