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有机化学
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有机化学 ›› 2013, Vol. 33 ›› Issue (02): 365-369.DOI: 10.6023/cjoc201210003 上一篇    下一篇

研究简报

小远志多糖一级结构的初步研究

陈良凤a, 周俊b, 宛瑜c, 吴翚a,c   

  1. a 江苏师范大学化学化工学院 徐州 221116;
    b 江苏恩华药业股份有限公司 徐州 221007;
    c 江苏省药物植物生物技术重点实验室 徐州 221116
  • 收稿日期:2012-10-05 修回日期:2012-11-13 发布日期:2012-11-23
  • 通讯作者: 吴翚 E-mail:wuhui72@yahoo.com.cn
  • 基金资助:

    江苏省高校自然科学(Nos. 10KJA430050, 11KJB150017)和江苏省普通高校研究生科研创新计划(No. CXZZ12_0979)资助项目.

Preliminary Study on the Primary Structure of Polygala sibirica L. var megalopha Fr. Polysaccrides

Chen Liangfenga, Zhou Junb, Wan Yuc, Wu Huia,c   

  1. a School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou 221116;
    b Jiangsu Nhwa Pharmaceutical Group, Xuzhou 221007;
    c Jiangsu Key Laboratory of Biotechnology on Medical Plant, Xuzhou 221116
  • Received:2012-10-05 Revised:2012-11-13 Published:2012-11-23
  • Supported by:

    Project supported by the Key Basic Research Project in Jiangsu University (Nos. 10KJA430050, 11KJB150017), and the Graduate Innovation Project in Jiangsu Province (No. CXZZ12_0979).

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从药用植物小远志中提取、精制得多糖PP-1, PP-2, 采用纸层析、薄层层析和气相色谱等方法确定了多糖中的单糖组成. 通过高碘酸氧化、Smith降解和甲基化分析等方法确定了相邻单糖基连接方式, 初步推测了两个小远志多糖可能的一级结构, 为进一步合成和研究其生物活性提供了数据支持.

关键词: 小远志多糖, 组成, 一级结构

Two polysaccharides PP-1 and PP-2 were isolated and purified from Polygala sibirica L. var megalopha Fr. Their constituents were analyzed by paper chromatography, thin-layer chromatography (TLC) and gas chromatography (GC), and the link typies between monosaccharides were determined via periodate-oxidation, Smith degradation and methylation etc. Then their possible primary structure was inferred for the further investigation of their synthesis and bioactivity.

Key words: Polygala sibirica L. var megalopha Fr. polysaccharide, composition, primary structure