微波辅助合成芳烃钌(II)配合物[(η6-RC6H5)Ru(m-MOPIP)Cl]Cl

doi:10.6023/cjoc201303022

有机化学 ›› 2013, Vol. 33 ›› Issue (9): 2022-2027.DOI: 10.6023/cjoc201303022 上一篇下一篇

研究简报

微波辅助合成芳烃钌(II)配合物[(η⁶-RC₆H₅)Ru(m-MOPIP)Cl]Cl

吴琼^a, 吴剑^a, 梅文杰^a, 姚骏骅^b, 吴韦黎^a, 陈燕华^a, 陶韵伊^a

a 广东药学院药科学院广州 510006;
b 中山大学测试中心广州 510275

收稿日期:2013-03-15 修回日期:2013-04-06 发布日期:2013-05-06
通讯作者: 梅文杰 E-mail:weijiemei@126.com
基金资助:
广东省科技计划(No. 2013J4100072);广州市科技计划(No. 7411791521750)资助项目

Microwave-Assisted Synthesis of Arene Ru(II) Complexes[(η⁶-RC₆H₅)Ru(m-MOPIP)Cl]Cl

Wu Qiong^a, Wu Jian^a, Mei Wenjie^a, Yao Junhua^b, Wu Weili^a, Chen Yanhua^a, Tao Yunyi^a

a School of Pharmacy, Guangdong Pharmaceutical University, Gongzhou 510006;
b Instrumental Analysis and Research Center, Sun Yat-sen University, Gongzhou 510275

Received:2013-03-15 Revised:2013-04-06 Published:2013-05-06
Supported by:
Project supported by the Science and Technology Planning Project of Guangdong Province (No. 2013J4100072) and the Science and Technology Planning Project of Guangzhou City (No. 7411791521750)

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摘要/Abstract

运用微波辅助合成技术, 在二氯甲烷溶液中, 60℃条件下, Pyrex管中微波辐射30 min制备得到芳烃钌(II)化合物[(η⁶-RC₆H₅)Ru(m-MOPIP)Cl]Cl (R=H 3a, R=CH₃ 3b; m-MOPIP=2-(3-甲氧苯基)-咪唑并[4,5f][1,10]菲啰啉), 反应产率分别为90%和91%, 目标化合物运用¹H NMR,¹³C NMR, IR, ESI-MS以及¹H-¹H COSY进行表征; 在相同条件下SiC管中, 屏蔽微波辐射对反应的影响, 3a和3b的产率分别为89%和90%, 说明微波“非热效应”对芳烃钌(II)配合物的合成没有显著影响.

关键词: 微波辅助合成, 2-(3-甲氧基苯基)-咪唑并[4,5f][1,10]菲啰啉, 芳烃钌(II)配合物

Two arene Ru(II) complexes[(η⁶-RC₆H₅)Ru(m-MOPIP)Cl]⁺ (R=H 3a, R=CH₃ 3b; m-MOPIP=2-(3-meth- oxyphenyl)imidazole[4,5-f][1,10]phenanthroline) were prepared under the microwave irradiation at 60 ℃ for 30 min in Pyrex vessel with the yield of about 90% and 91%, and the target compounds were characterized by ¹H NMR,¹³C NMR, IR, ESI-MS and ¹H-¹H COSY spectra. At the same reaction conditions, application of SiC vessel to screen the effect of microwave irradiation, 3a and 3b were obtained with the yield of about 89% and 90%. These results indicated that the microwave "non-thermal effect" has no obvious influence on the synthesis of arene Ru(II) complexes.

Key words: microwave-assisted synthesis, 2-(3-methoxyphenyl)imidazole[4,5f][1,10]phenanthroline, arene Ru(II) complexes

引用此文

吴琼, 吴剑, 梅文杰, 姚骏骅, 吴韦黎, 陈燕华, 陶韵伊. 微波辅助合成芳烃钌(II)配合物[(η⁶-RC₆H₅)Ru(m-MOPIP)Cl]Cl[J]. 有机化学, 2013, 33(9): 2022-2027.

Wu Qiong, Wu Jian, Mei Wenjie, Yao Junhua, Wu Weili, Chen Yanhua, Tao Yunyi. Microwave-Assisted Synthesis of Arene Ru(II) Complexes[(η⁶-RC₆H₅)Ru(m-MOPIP)Cl]Cl[J]. Chin. J. Org. Chem., 2013, 33(9): 2022-2027.

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微波辅助合成芳烃钌(II)配合物[(η⁶-RC₆H₅)Ru(m-MOPIP)Cl]Cl

Microwave-Assisted Synthesis of Arene Ru(II) Complexes[(η⁶-RC₆H₅)Ru(m-MOPIP)Cl]Cl

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