铱催化简单醚导向的环丙烷类化合物对映选择性C(sp3)—H硼化反应

doi:10.6023/cjoc202300023

有机化学 ›› 2023, Vol. 43 ›› Issue (4): 1605-1607.DOI: 10.6023/cjoc202300023 上一篇下一篇

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铱催化简单醚导向的环丙烷类化合物对映选择性C(sp³)—H硼化反应

王文芳^a^,^*(), 孙伟^b^,^*()

a 西北民族大学化工学院环境友好复合材料国家民委重点实验室甘肃省高校环境友好复合材料及生物质利用重点实验室甘肃省生物质功能复合材料工程研究中心兰州 730000
b 中国科学院兰州化学物理研究所羰基合成与选择氧化国家重点实验室兰州 730000

发布日期:2023-04-25
通讯作者: 王文芳, 孙伟

Iridium-Catalyzed Enantioselective C(sp³)—H Borylation of Cyclopropanes with Simple Ether as Directing Groups

Wenfang Wang^a(), Wei Sun^b()

a Gansu Provincial Biomass Function Composites Engineering Research Center, Key Laboratory for Utility of Environment-Friendly Composite Materials and Biomass in University of Gansu Province, Key Laboratory of Environment-Friendly Composite Materials of the State Ethnic Affairs Commission, College of Chemical Engineering, Northwest Minzu University, Lanzhou 730000
b State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000

Published:2023-04-25
Contact: Wenfang Wang, Wei Sun

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王文芳, 孙伟. 铱催化简单醚导向的环丙烷类化合物对映选择性C(sp³)—H硼化反应[J]. 有机化学, 2023, 43(4): 1605-1607.

Wenfang Wang, Wei Sun. Iridium-Catalyzed Enantioselective C(sp³)—H Borylation of Cyclopropanes with Simple Ether as Directing Groups[J]. Chinese Journal of Organic Chemistry, 2023, 43(4): 1605-1607.

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图/表 4

图式1. 作者的辅助催化设想

Scheme 1. Author?s hypothesis

图式2. 环丙烷C(sp3)—H不对称硼化反应条件优化

Scheme 2. Optimization of enantioselective C(sp3)—H borylation of cyclopropane

图式3. 部分手性双齿硼基配体(CBLs)

Scheme 3. Representative CBL ligands

图式4. 部分底物拓展

Scheme 4. Representative substrates scope

参考文献 8

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铱催化简单醚导向的环丙烷类化合物对映选择性C(sp³)—H硼化反应

Iridium-Catalyzed Enantioselective C(sp³)—H Borylation of Cyclopropanes with Simple Ether as Directing Groups

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