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有机化学
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有机化学 ›› 2003, Vol. 23 ›› Issue (2): 195-197. 上一篇    下一篇

研究论文

N－5－四唑基－N′－芳甲酰基脲的合成及其生物活性

汪焱钢;龚银香;赵新筠;叶文法;王胜   

  1. 华中师范大学化学系,武汉(430079)
  • 发布日期:2003-02-25

Synthesis and biological activity of N-5-tetrazolyl－N′－aryl formyl urea

Wang Yangang;Gong Yinxiang;Zhao Xinyun;Ye Wenfa;Wang Sheng   

  1. Department of Chemistry,Central China Normal University,Wuhan (430079)
  • Published:2003-02-25

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合成了15个新的含四唑的基的芳甲酰基脲类化合物，用IR，^1H NMR和元素分 析证实了它们的结构，并进行了初步的生物活性试验，生测结果证明一些目标化合 物具有优良的植物生长调节活性，其中N－5－四唑基－N′－芳甲酰基脲（2h)和N －5－四唑基－N′－对溴苯基甲酰基脲（2j)具有很好的生长素活性，2h,2j和N－ 5－四唑基－N′－对甲基苯基甲酰基脲（2m）具有优良的细胞分裂素活性。

关键词: 四唑 P;脲;红外分光光度法;质子磁共振谱法;生物活性;植物生长条件剂, 细胞分裂素

Fifteen new aryl formyl ureas containing tetrazolyl have been synthesized. Their structures were confirmed by IR, 1H NMR and elementary analysis. The results of biological activity tests make clear that some target compounds have evident activity on plant growth regulator. Particularly, N-5-tetrazolyl-N'-p-methoxyphenyl formyl urea (2h) and 7V-5-tetrazolyl-.N'-p-bromophenyl formyl urea (2j) have good auxins activity, 2h, 2j and N-5-tetrazolyl-N'-p-methylphenyl formyl urea (2m) have excellent activity of cytokinin.

Key words: TETRAZOLE P;UREA;IR;1HNMR;BIOLOGICAL ACTIVITY;PLANT GROWTH REGULATORS, CYTOKININ

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