有机化学 ›› 2005, Vol. 25 ›› Issue (9): 1045-1048. 上一篇    下一篇

研究论文

硫酸亚铈催化的芳香化合物与苄基醇、烯丙醇类化合物以及苄基氯的傅-克烷基化反应研究

李金恒*,刘文杰,梁云,谢叶香   

  1. (湖南师范大学化学化工学院 化学生物学与中药分析重点实验室 长沙 410081)
  • 收稿日期:2004-07-09 修回日期:2005-03-15 发布日期:2005-08-24
  • 通讯作者: 李金恒

Ce2(SO4)3-Catalyzed Friedel-Crafts Alkylation of Aromatic Compounds with Benzyl Alcohols, Allyl Alcohols and Benzyl Chlorides

LI Jin-Heng*,LIU Wen-Jie,LIANG Yun,XIE Ye-Xiang   

  1. (Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, College of Chemistry and Chemical
    Engineering, Hunan Normal University, Changsha 410081)
  • Received:2004-07-09 Revised:2005-03-15 Published:2005-08-24
  • Contact: LI Jin-Heng

硫酸亚铈作为一种便宜的和有效的催化剂催化芳香化合物与苄基醇、烯丙醇类化合物和苄基氯的傅-克烷基化反应. 在1~10 mol%的硫酸亚铈存在下, 芳香化合物分别与苄基醇、烯丙醇类化合物和苄基氯能够顺利有效地进行傅-克烷基化反应. 此外, 催化剂能回收, 再次使用三次也没有明显地失去催化活性.

关键词: 苄基醇, 烯丙醇类化合物, 傅-克烷基化反应, 苄基氯, 硫酸亚铈, 芳香化合物

Ce2(SO4)3 was used as an inexpensive and effective catalyst for the Friedel-Crafts alkylation of aromatic compounds with benzyl alcohols, allyl alcohols and benzyl chlorides. In the presence of 1~10 mol% of Ce2(SO4)3, Friedel-Crafts alkylation reactions of aromatic compounds with benzyl alcohols, allyl alcohols and benzyl chlorides were carried out smoothly and efficiently. Moreover, the catalyst could be recovered and reused three times without significant loss of activity.

Key words: allyl alcohol, Friedel-Crafts alkylation, aromatic compound, benzyl chloride, benzyl alcohol, Ce2(SO4)3