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有机化学
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有机化学 ›› 2006, Vol. 26 ›› Issue (11): 1553-1556. 上一篇    下一篇

研究论文

光学纯7,7′-二取代联二萘酚催化乙基锌对醛的对映选择性加成

刘全忠*，谢南生   

  1. (西华师范大学化学化工学院 南充 637002)
  • 收稿日期:2005-08-17 修回日期:1900-01-01 发布日期:2006-10-27
  • 通讯作者: 刘全忠

Optically Pure 7,7′-Disubstituted Binaphthols Catalyzed Enantioselective Addition of Diethylzinc to Aldehydes

LIU Quan-Zhong*,XIE Nan-Sheng   

  1. (College of Chemistry and Chemical Engineering, China West Normal University, Nanchong 637002)
  • Received:2005-08-17 Revised:1900-01-01 Published:2006-10-27
  • Contact: LIU Quan-Zhong

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815

被引次数

3

合成了一类光学纯的7,7′-二取代联二萘酚, 并将其用在乙基锌对醛的对映选择性加成, 以54%～88%的产率和最高88%的对映选择性得到了光学活性的1-苯基-1-丙醇.

关键词: 7,7′-二取代联二萘酚, 对映选择性加成, 1-苯基-1-丙醇

Optically pure 7,7′-disubstituted binaphthols were synthesized and used in the enantioselective addition of diethyl zinc to aldehydes to afford the corresponding alcohols with 54%～88% yields and up to 88% ee.

Key words: enantioselective addition, 1-phenyl-1-propanol, 7,7′-disubstituted binaphthol