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有机化学
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有机化学 ›› 2006, Vol. 26 ›› Issue (9): 1232-1238. 上一篇    下一篇

研究论文

2-氰基-3-取代吡啶甲胺基-3-取代丙烯酸乙氧乙酯的合成和除草活性研究

刘玉秀，李姮，赵奇奇，汪清民*，黄润秋   

  1. (南开大学元素有机化学研究所 元素有机化学国家重点实验室 天津 300071)
  • 收稿日期:2005-08-05 修回日期:1900-01-01 发布日期:2006-09-11
  • 通讯作者: 汪清民

Synthesis and Herbicidal Activity of Ethoxyethyl 2-Cyano-3- (substituted)pyridinemethylamino-3-(substituted)acrylates

LIU Yu-Xiu,LI Heng,ZHAO Qi-Qi,WANG Qing-Min*,HUANG Run-Qiu   

  1. (State Key Laboratory of Elemento-organic Chemistry, Institute of Elemento-organic Chemis-try,
    Nankai University, Tianjin 300071)
  • Received:2005-08-05 Revised:1900-01-01 Published:2006-09-11
  • Contact: WANG Qing-Min

PDF

1172

被引次数

19

一系列2-氰基-3-取代吡啶甲胺基丙烯酸酯被合成作为光合作用光系统II电子传递抑制剂. 生测发现一些目标化合物表现出很好的除草活性, 如(Z)-2-氰基-3-异丙基-3-(2-烷氧基取代的吡啶-3-基)甲胺基丙烯酸乙氧乙酯. 生测结果表明在吡啶环的2位合适的取代基和丙烯酸酯的3位取代基的体积对除草活性至关重要.

关键词: 氰基丙烯酸酯, 吡啶环, 光系统II, 除草活性, 电子传递抑制剂

A series of 2-cyano-3-(substituted)pyridinemethylaminoacrylates were synthesized as herbicidal inhibitors of photosystem II (PSII) electron transport and their herbicidal activities were evaluated. Some of them exhibited excellent herbicidal activities, especially (Z)-ethoxyethyl 2-cyano-3-isopropyl-3-(2- alkoxypyridin-3-yl)methaneaminoacrylate. These results indicated that a suitable substituent at the 2-position of pyridine ring and a well-fit group at the 3-position of acrylate were both essential for high her-bicidal activity.

Key words: photosystem II (PSII), pyridine ring, electron transport inhibitor, herbicidal activity, cyanoacrylate