有机化学 ›› 2007, Vol. 27 ›› Issue (08): 1013-1017. 上一篇    下一篇

研究简报

五元氮杂糖衍生物的实用有效合成方法

李小六*,张平竹,田军,段科芳,陈华   

  1. (河北大学化学与环境科学学院 保定 071002)
  • 收稿日期:2006-07-26 修回日期:1900-01-01 发布日期:2007-07-30
  • 通讯作者: 李小六*

A Practical and Efficient Synthesis of Five-Membered Azasugar Derivatives

LI Xiao-Liu*, ZHANG Ping-Zhu, TIAN Jun, DUAN Ke-Fang, CHEN Hua   

  1. (School of Chemistry and Environmental Sciences, Hebei University, Baoding 071002)
  • Received:2006-07-26 Revised:1900-01-01 Published:2007-07-30
  • Contact: LI Xiao-Liu*

以D-葡萄糖为原料, 经具有降冰片烷结构的双环缩醛中间体, 合成了部分羟基保护的1-脱氧-D-氮杂阿拉伯糖衍生物, 提供了一种合成五元氮杂糖衍生物的简便有效方法.

关键词: D-葡萄糖, 降冰片烷结构, 五元环氮杂糖

A practical and efficient synthesis of 1,4-dideoxy-1,4-imino-D-arabinol and its partially protected derivatives has been described via the key intermediate with a norbornane-like structure using D-glucose as a starting material.

Key words: norbornane-like structure, five membered azasugar, D-glucose