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有机化学
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有机化学 ›› 2007, Vol. 27 ›› Issue (08): 918-924. 上一篇    下一篇

综述与进展

DNA光解酶模型研究的近期进展

季学保，宋钦华*   

  1. (中国科学技术大学化学系 合肥230026)
  • 收稿日期:2006-05-29 修回日期:1900-01-01 发布日期:2007-07-30
  • 通讯作者: 宋钦华*

Recent Progress in Model Studies of Mechanism for DNA Photolyase

JI Xue-Bao, SONG Qin-Hua*   

  1. (Department of Chemistry, University of Science and Technology of China, Hefei 230026)
  • Received:2006-05-29 Revised:1900-01-01 Published:2007-07-30
  • Contact: SONG Qin-Hua*

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1289

被引次数

8 | 2

用模型化合物来模拟DNA光解酶与底物的作用, 有助于认识DNA光复活作用机理. 评述了环丁烷型嘧啶二聚体光解酶和(6-4)光产物光解酶的模型研究进展, 并展望了该领域的发展前景．

关键词: DNA光解酶, 环丁烷型嘧啶二聚体, 模型研究, (6-4)光产物

The information for the mechanism of DNA photolyase can be obtained by using model compounds to mimic the repair process of DNA photoreactivation. In this paper, recent progresses in model studies of cyclobutane pyrimidine dimer photolyases and (6-4)photoproduct photolyases have been reviewed.

Key words: model study, cyclobutane pyrimidine dimer, (6-4)photoproduct, DNA photolyase