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有机化学
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有机化学 ›› 2008, Vol. 28 ›› Issue (10): 1756-1760. 上一篇    下一篇

研究论文

邻位锂化方法简便高效地合成邻羟基芳香醛: 在线红外在邻位锂化方法中的应用

郝小燕a ; 周智明*,a ; 薛为哲a ; 殷 杰a 徐宝财b   

  1. (a北京理工大学化工与环境学院 北京 100081)
    (b北京工商大学化学与环境工程学院 北京 100037)
  • 收稿日期:2008-03-11 修回日期:2008-05-04 发布日期:2008-10-20
  • 通讯作者: 周智明

A Feasible and Efficient Route for Preparation of ortho-Hydroxy- benzaldehydes: Application of ortho-Lithiation Method and in-situ FTIR Spectroscopy

HAO, Xiao-Yana ; ZHOU, Zhi-Ming*,a ; XUE, Wei-Zhea ; YIN, Jiea; XU, Bao-Caib   

  1. (a School of Chemical Engineering & the Environment, Beijing Institute of Technology, Beijing 100081)
    (b School of Chemical & Environmental Engineering, Beijing Technology & Business University, Beijing 100037)
  • Received:2008-03-11 Revised:2008-05-04 Published:2008-10-20
  • Contact: ZHOU, Zhi-Ming

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被引次数

3

利用DMF作亲电试剂通过对芳香羰基化合物邻位锂化的方法区域选择性地合成了一系列邻羟基芳香醛, 并且利用原位红外监测了反应过程, 证明了反应过程中间体六元锂络合物的存在.

关键词: 邻羟基芳香醛, 邻位锂化, 在线红外

Ortho-lithiated O-phenyl carbamates treated by DMF offered a feasible general route to construct ortho-hydroxybenzaldehydes regioselectively, and in-situ IR monitoring the process implied the existence of the six-membered intermediate Li-complex.

Key words: ortho-lithiation, ortho-hydroxybenzaldehyde, in-situ FTIR