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有机化学
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有机化学 ›› 2008, Vol. 28 ›› Issue (10): 1813-1815. 上一篇    下一篇

研究简报

1-苯基-5-芳基-1,2-二氢-1,2,4-三唑-3-硫酮的合成

刘天宝*,a ; 彭艳芬a ; 邹建平b   

  1. (a池州学院化学与食品科学系 池州 247000)
    (b苏州大学化学化工学院 苏州 215123)
  • 收稿日期:2007-11-11 修回日期:2008-04-25 发布日期:2008-10-20
  • 通讯作者: 刘天宝

Synthesis of 1-Phenyl-5-aryl-1,2-dihydro-1,2,4-triazole-3-thione Derivatives

LIU, Tian-Bao*,a ; PENG, Yan-Fen a; ZOU, Jian-Pingb   

  1. (a Department of Chemistry and Food Science, Chizhou College, Chizhou 247000)
    (b Department of Chemistry, Suzhou University, Suzhou 215123)
  • Received:2007-11-11 Revised:2008-04-25 Published:2008-10-20
  • Contact: LIU, Tian-Bao

PDF

1477

被引次数

23

将取代苯甲酰氯1a～1f与硫氰酸钾反应, 得到的中间体不需纯化直接与苯肼反应, 成功地合成了1-苯基-5-芳 基-1,2-二氢-1,2,4-三唑-3-硫酮(2a～2f). 化合物2的结构通过红外光谱、核磁共振光谱和高分辨质谱进行了表征.

关键词: 1,2,4-三唑-3(2H)-硫酮, 取代苯甲酰氯, 苯肼

Substituted benzoyl chlorides were reacted with potassium isothiocyanate, and the resulting intermediates were then reacted with phenyl hydrazine to give the title compounds 1-phenyl-5- aryl-1,2-dihydro-1,2,4-triazole-3-thione derivatives. Their structures were characterized by IR, 1H NMR, 13C NMR and HRMS data.

Key words: substituted benzoyl chloride, 1,2,4-triazole-3(2H)-thione, phenylhydrazine