双子季铵盐稳定的纳米钯催化Suzuki反应的研究

有机化学 ›› 2011, Vol. 31 ›› Issue (06): 850-854. 上一篇下一篇

研究论文

双子季铵盐稳定的纳米钯催化Suzuki反应的研究

周波，李毅群*

(暨南大学化学系广州 510632)

收稿日期:2010-09-11 修回日期:2010-12-30 发布日期:2011-02-14
通讯作者: 李毅群 E-mail:tlyq@jnu.edu.cn

Suzuki Reaction Catalyzed by Nanopalladium Stabilized by Gemini Quaternary Ammonium Salt

ZHOU Bo, LI Yi-Qun

(Department of Chemistry, Jinan University, Guangzhou 510632)

Received:2010-09-11 Revised:2010-12-30 Published:2011-02-14
Contact: Li Yi-Qun E-mail:tlyq@jnu.edu.cn

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摘要/Abstract

双子座季铵盐能够稳定现场产生的纳米钯粒子, 该纳米钯粒子能有效地催化一系列芳基硼酸和芳基卤代烃发生Suzuki偶联反应. 双子座季铵盐稳定的纳米钯粒子能够在空气中稳定存在, 透射电镜(TEM)分析纳米钯粒子呈圆球形, 粒径分布在5～25 nm. 该方法具有反应条件温和、反应时间短、后处理简单方便等优点.

关键词: Suzuki 反应, 纳米钯, 双子座季铵盐

Palladium nanoparticles with the size ranged from 5 nm to 25 nm confirmed by transmission electron microscopy (TEM), generated in situ from the reaction of palladium(II) chloride and stabilized by Gemini quaternary ammonium salt, have been demonstrated to be an ef?cient catalyst for Suzuki car-bon-carbon cross coupling reaction. A variety of aryl bronic acids and aryl halides have been proceed smoothly to afford the corresponding biaryls in high yields by using palladium nanoparticles in the presence of potassium carbonate without any ligands. This protocol has the merits of that the catalyst is stable in air and the procedure of experiment is simple.

Key words: Suzuki reaction, nanopalladium, Gemini quaternary ammonium salt

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周波, 李毅群. 双子季铵盐稳定的纳米钯催化Suzuki反应的研究[J]. 有机化学, 2011, 31(06): 850-854.

ZHOU Bo, LI Yi-Qun. Suzuki Reaction Catalyzed by Nanopalladium Stabilized by Gemini Quaternary Ammonium Salt[J]. Chin. J. Org. Chem., 2011, 31(06): 850-854.

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双子季铵盐稳定的纳米钯催化Suzuki反应的研究

Suzuki Reaction Catalyzed by Nanopalladium Stabilized by Gemini Quaternary Ammonium Salt

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