有机化学 ›› 2003, Vol. 23 ›› Issue (12): 1416-1418. 上一篇    下一篇

研究论文

无溶剂、无催化剂条件下5-[(3-吲哚基)-芳甲基]-2,2-二甲基-l,3-二氧六环-4,6-二酮的合成

王春;张英群;李贵深;李敬慈;李晓陆   

  1. 河北农业大学理学院
  • 发布日期:2003-12-25

Synthesis of 5- [ (Indol-3-yl) -arylmethyl ] -2,2-dimethyl-l, 3- dioxane-4,6-dione without Solvent and Catalyst

Wang Chun;Zhang Yingqun;Li Guishen;Li Jingci;Li Xiaoliu   

  1. College of Science,Agricultural University of Hebei
  • Published:2003-12-25

在无溶剂和催化剂条件下,由芳香醛、吲哚、丙二酸亚异丙酯的三组分缩合反 应,制备了5.[(3-吲哚基)-芳甲基]-2,2-二甲基-1,3-二氧六环-4,6-二酮,产 率为70%~85%,产物结构经~1H NMR,IR确证.

关键词: 吲哚 P;二氧六环 P;芳香族醛;丙二酸亚异丙酯;缩合反应;质子磁共振谱法, 红外分光光度法

A convenient three component condensation of indole with aromatic aldehydes and isopropylidene malonate without solvent and catalyst is described. The yields are ranged in 70% ~ 85% . The structures of the products were identified by 1R NMR and IR spectra.

Key words: INDOLE P;DIOXANE P;aromatic aldehyde;isopropylidene malonate, CONDENSATION REACTION;1HNMR;IR

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