有机化学 ›› 2003, Vol. 23 ›› Issue (8): 858-860. 上一篇    下一篇

研究论文

无溶剂条件下5-亚烃基硫代巴比妥酸的合成

李贵深;王春;李敬慈;张英群;李晓陆   

  1. 河北农业大学理学院
  • 发布日期:2003-08-25

Synthesis of 5-Arylmethylene Thiobarbituric Acids under Solvent- Free Conditions

Li Guishen;Wang Chun;Li Jingci;Zhang Yingqun;Li Xiaolu   

  1. College of Science, Agricultural University of Hebei
  • Published:2003-08-25

在无溶液和催化剂条件下,采用室温研磨、加热和微波辐射的方法,由芳香醛 和硫代巴比妥酸经Knoevenagel固相缩合反应高效率地制备了5-亚烃基硫代巴比妥 酸,产物结构经~1H NMR,~(13)C NMR和IR确证。

关键词: 微波辐射;亚烃基硫代巴比妥酸;芳香族醛;质子磁共振谱法;碳十三核磁共振谱法, 红外分光光度法

5-Arylmethylene thiobarbituric acids have been efficiently prepared by Knoevenagel condensation of aromatic aldehydes and thiobarbituric acid under the solid state conditions of grinding at room temperature, or heating, or microwave irradiation without organic solvent and catalyst. The products were identified by ~1 NMR,~(13)C NMR and IR spectra

Key words: MICROWAVE RADIATION, arylidene thiobarbituric acid, aromatic aldehyde, 1HNMR, C13NMR, IR

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