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有机化学
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有机化学 ›› 1996, Vol. 16 ›› Issue (1): 78-82. 上一篇    下一篇

研究论文

通过硼氢化-原位再结晶提高二异松莰烷基硼烷光学纯度的简便方法

赵德杰;乐融融;单自兴   

  1. 武汉大学化学系
  • 发布日期:1996-02-25

A convenient method for upgrading the optical purity of diisopinocampheylborane via hydroboration-in situ recrystallization

ZHAO DEJIE;LE RONGRONG;SHAN ZIXING   

  • Published:1996-02-25

被引次数

7

本文叙述了由国产低光学纯(43.6%e e)(-)-α-蒎烯通过硼氢化-原位再结晶, 制备高光学纯(97.2%ee)(+)-二异松茨烷基硼烷(diisopinocampheylborane, Ipc2BH)的简便新方法。

关键词: 蒎烯, 再结晶, 光学纯度, 硼氢化, 二异松莰烷基硼烷

This paper describes a convenient method for the preparation of diisopinocampheylborane(+)-Ipc2BH) with high optical purity (up to 97.2%) from commercially availale (-)-α-pinene with low optical purity (43.6%). After examining various reaction parameters, it was found that under the optimum conditions, (Table 1, entry 9) the crystalline product (+)-Ipc2BH of 97.2% e e was obtained in 44.5% yield by using hydroboration-in situ recrystallization procedure as shown in Scheme 2.

Key words: PINENE, RECRYSTALLIZATION

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