有机化学 ›› 2000, Vol. 20 ›› Issue (1): 88-90. 上一篇    下一篇

研究论文

微波作用下2-烃基-4-喹啉酮的简便合成法

黄志真;吴露玲;黄宪   

  1. 浙江大学西溪校区化学系
  • 发布日期:2000-02-25

Facile synthesis of 2- alkyl and 2- aryl -4- quinolones using microwave irradiation

Huang Zhizhen;Wu Luling;Huang Xian   

  • Published:2000-02-25

在微波作用下5-(甲硫亚烃基)丙二酸亚异丙酯可与芳胺发生加成消除反应,首先生成5-(芳胺基亚烃基)丙二酸亚异丙酯,继而进一步闭环,提供了2-烃基-4-喹啉酮的快速合成法。

关键词: 喹啉酮P, 微波技术, 芳香族胺, 丙二酸P, 异丙酯P

The addition - elimination of 5- methylthioalkylidene isopropylidene malonates with arylamines, followed by cyclization, can take place easily under microwave irradiation conditions to provide a tacile access to 2- alkyl and 2-aryl -4- quinolones.

Key words: QUINOLINONE P, MICROWAVE TECHNIQUE, AROMATIC AMINES, MALONIC ACID P, ISOPROPYL ESTER

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