有机化学 ›› 2000, Vol. 20 ›› Issue (5): 827-829. 上一篇    下一篇

研究论文

2-(取代苯亚氨次甲基)吲哚衍生物的质谱研究

徐莉;徐世平;徐嵩;李兰敏   

  1. 中国医学科学院;中国协和医科大学药物研究所
  • 发布日期:2000-10-25

Mass spectroscopic study of 2-(substituted phenyliminomethylene) indole derivatives

Xu Li;Xu Shiping;Xu Song;Li Lanmin   

  • Published:2000-10-25

报道了由吲哚-2-甲醛和取代苯胺进行亲核加成反应合成了22个2-(取代苯亚氨次甲基)吲哚衍生物,主要对本类化合物的两种质谱特殊裂解过程进行了分析研究。

关键词: 吲哚P, 裂解, 质谱法, 高分辨率

Twenty two 2-(substituted phenyliminomethylene)indole derivatives were synthesized via nucleophilic addition reaction of indole-2- formaldehyde with different substituted anilines. The structures of these derivatives were confirmed by ^1H NMR and MS data. Two special clevage patlerns in the formation of the specific fragment ions in the MS of 2-(substituted phenyliminomethylene) indoles are discussed in detail.

Key words: INDOLE P, PYROLYSIS, MASS SPECTROGRAPHY, HIGH RESOLUTION

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