辐射接枝共聚合反应及其在有机生物医用材料制备中的应用

摘要/Abstract

γ-射线辐射高分子材料表面接枝共聚合是一种绿色的、重要的有机生物材料合成制备方法. 综述了γ-射线辐射接枝共聚反应的原理、特点, 阐述了预辐射接枝共聚和共辐射接枝共聚的方法, 介绍了当前γ-射线辐射接枝共聚反应在改善有机生物医用材料的表面亲水性、生物相容性等方面的应用. 对辐射接枝共聚合制备功能药物载体研究进行了简要介绍.

关键词: γ-射线, 有机生物医用材料, 辐射接枝共聚, 共辐射, 预辐射

Irradiation graft copolymerization becomes a green and important synthetic strategy for surface functionalization and facile preparation of new organic biomedical materials. This article reviews the principles and features of γ-ray irradiation graft copolymerization, and summarizes the biomedical applications of irradiation graft copolymerization to tailor surface from hydrophobicity to hydrophilicity, and their functionalization. Furthermore, as novel synthetic approach, the irradiation copolymerization was also employed to prepare new materials as functional drug carrier with controlled release.

Key words: irradiation graft copolymerization, organic biomedical materials, pre-irradiation, mutual radiation, γ-ray

引用此文

张涛,侯小东,曹阿民^{b. 辐射接枝共聚合反应及其在有机生物医用材料制备中的应用[J]. 有机化学, 2006, 26(9): 1328-1334.}

ZHANG Tao^a,b,HOU Xiao-Dong^a,b,CAO A-Min*^,b. Irradiation Graft Copolymerization and Its Application forPreparation of Organic Biomedical Materials[J]. Chin. J. Org. Chem., 2006, 26(9): 1328-1334.

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