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有机化学
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有机化学 ›› 2008, Vol. 28 ›› Issue (9): 1620-1623. 上一篇    下一篇

研究简报

川麦冬皂苷类化学成分的研究

王建忠* ; 陈小兵; 王锋鹏   

  1. (四川大学华西药学院天然药物系 成都 610041)
  • 收稿日期:2008-01-09 修回日期:2008-02-27 发布日期:2008-09-20
  • 通讯作者: 王建忠

Structural Elucidation of Steroidal Glycosides from Ophiopogon japonicus

WANG, Jian-Zhong*; CHEN, Xiao-Bing ; WANG, Feng-Peng   

  1. (Department of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu 610041)
  • Received:2008-01-09 Revised:2008-02-27 Published:2008-09-20
  • Contact: WANG, Jian-Zhong

PDF

1625

被引次数

30

从川麦冬[Ophiopogon japonicus (Thunb.) Ker-Gawl.]中分离得到四个皂苷类成分, 分别鉴定为14-hydroxy sprengerinin C (1), sprengerinin C (2), ophiogenin-3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (3)和β-胡萝卜苷(4, β-sitosterol β-D-glucopyranoside). 其中14-hydroxy sprengerinin C为新的C27甾体皂苷, 化合物sprengerinin C为首次从该植物分离得到. 运用现代波谱技术, 包括二维核磁共振谱和高分辨质谱, 对上述化合物的结构进行了确证.

关键词: 川麦冬, 百合科, 14-hydroxy sprengerinin C, C27甾体皂苷

A new steroidal 14-hydroxy sprengerinin C (1) was isolated from the tuber of Ophiopogon japonicus (Thunb.) Ker-Gawl., along with three known compounds, sprengerinin C (2), ophiogenin-3-O-α-L- rhamnopyranosyl-(1→2)-β-D-glucopyranoside (3) and β-sitosterol-β-D-glucopyranoside (4). Their struc-tures were established on the basis of IR, HR-MS, 1D and 2D-NMR analyses, as well as by literature com-parison of spectroscopic data.

Key words: Ophiopogon japonicus, C27-steroidal glycoside, 14-hydroxy sprengerinin C, liliaceae