有机化学 ›› 2012, Vol. 32 ›› Issue (11): 2054-2062.DOI: 10.6023/cjoc201205021 上一篇    下一篇

综述与进展

环糊精-石墨烯超分子体系

孙涛a, 李建业b, 郝爱友a   

  1. a 山东大学化学与化工学院 济南 250100;
    b 潍坊科技学院 潍坊 262700
  • 收稿日期:2012-05-17 修回日期:2012-06-05 发布日期:2012-06-13
  • 通讯作者: 郝爱友 E-mail:haoay@sdu.edu.cn

Cyclodextrin-Graphene Supramolecular System

Sun Taoa, Li Jianyeb, Hao Aiyoua   

  1. a School of Chemistry & Chemical Engineering, Shandong University, Jinan 250100;
    b Chemical Engineering Department, Weifang University of Science and Technology, Weifang 262700
  • Received:2012-05-17 Revised:2012-06-05 Published:2012-06-13

环糊精是由D型吡喃葡萄糖通过α-1,4-糖苷键连接而成的环状超分子主体化合物, 其特殊的结构赋予了其良好的分子识别性能; 石墨烯是仅由单层sp杂化的碳原子构筑的具有良好的电化学性能的材料. 作为著名的“明星分子”, 石墨烯类材料无疑是近5年来研究热点之一. 在各种各样的石墨烯材料中, 由环糊精-石墨烯联合构筑的超分子体系在保留二者优良性能的同时又引入了新的功能特点. 综述了近些年来新发展起来的环糊精-石墨烯超分子体系: 通过二者作用方式进行了分类, 分为共价键连接和非共价键连接; 综述了该超分子体系在药物运输及释放、电化学检测(包括对药物分子、污染物和生物分子的检测)等领域的应用; 最后对该体系在药物负载及释放、模拟生物固氮、燃料电池、研究电子传导等应用前景进行了展望.

关键词: 环糊精, 石墨烯, 超分子化学, 药物运输, 电化学检测

Cyclodextrins, composed by D-glucose units linked by α-1,4-glucose bonds, have excellent molecule recognition ability for their particular structures. Graphene is a class of materials with good electrochemistry properties composed by one-atom-thick planar sheets of sp-bonded carbon atoms. As a famous “rising star”, graphene is the hot topics in recent five years. Among the various graphene materials, cyclodextrin-graphene supramolecular systems can combine their advantages and also introduce novel properties. This paper reviews the recent research condition of the cyclodextrin-graphene supramolecular systems: the system is classified into covalently-bonded and non-covalently-bonded systems for the interaction modes; The applications in drug carrying & release and electrochemistry detection (including drug molecules, pollutant and biomolecules) are reviewed; The prospects in the area of drug loading and release, mimic of bio-nitrogen-fixation-process, fuel cell and electron conducting study are raised.

Key words: cyclodextrin, graphene, supramolecular chemistry, drug transport, electrochemistry detection