有机化学 ›› 2017, Vol. 37 ›› Issue (1): 226-231.DOI: 10.6023/cjoc201607007 上一篇    下一篇

研究简报

碳酸银介导的芳胺氧化脱氢偶联制备芳香偶氮化合物

安玉龙, 谭鸿儒, 赵圣印   

  1. 东华大学化学化工与生物工程学院 上海 201620
  • 收稿日期:2016-07-05 修回日期:2016-08-17 发布日期:2016-09-01
  • 通讯作者: 赵圣印 E-mail:syzhao8@dhu.edu.cn
  • 基金资助:

    上海市科学自然基金(No. 15ZR1401400)以及中央高校教育基金(Nos. CUSF-DH-D-2016028,BCZD2016004)资助项目.

Ag2CO3 Mediated Oxidative Dehydrogenative Coupling of Anilines Giving Aromatic Azo Compounds

An Yulong, Tan Hongru, Zhao Shengyin   

  1. College of Chemistry, Chemical and Biological Engineering, Donghua University, Shanghai 201620
  • Received:2016-07-05 Revised:2016-08-17 Published:2016-09-01
  • Supported by:

    Project supported by the Natural Science Foundation of Shanghai Municipality(No. 15ZR1401400) and the Fundamental Research Funds for the Central Universities from the Ministry of Education of China(Nos. CUSF-DH-D-2016028, BCZD2016004).

芳香偶氮化合物广泛应用于有机染料、生物医药、食品添加剂、自由基诱发剂等领域.本工作以芳胺类化合物为原料,在叔丁醇钾的辅助作用下,通过碳酸银催化氧化作用,在氯苯溶剂中脱氢氧化偶联,高效合成一系列芳香偶氮类化合物,收率最高达92%.该方法操作简单,反应条件温和,为芳香偶氮类化合物的合成提供了一种高效且实用的路径.

关键词: 芳胺, 碳酸银, 叔丁醇钾, 芳香偶氮化合物

Aromatic azo compounds are widely used as organic dyes,biological medicines,food additives,radical initiators and so on.This paper describes an efficient protocol for the synthesis of aromatic azo compounds from anilines via Ag2CO3 mediated oxidative dehydrogenative coupling reactions in the presence of(CH3)3COK in PhCl.The yields are up to 92%,and this method is easy-operation and provides a practical process to synthesize aromatic azo compounds under mild conditions.

Key words: anilines, Ag2CO3, (CH3)3COK, aromatic azo compounds