有机化学 ›› 2017, Vol. 37 ›› Issue (8): 1916-1923.DOI: 10.6023/cjoc201703039 上一篇    下一篇

综述与进展

亚硝酸叔丁酯参与C—N键构建的研究进展

魏文廷, 朱文明, 吴益, 黄依铃, 梁洪泽   

  1. 宁波大学材料科学与化学工程学院 宁波 315211
  • 收稿日期:2017-03-23 修回日期:2017-04-18 发布日期:2017-05-10
  • 通讯作者: 魏文廷 E-mail:weiwenting@nbu.edu.cn
  • 基金资助:

    宁波大学人才引进基金(No.ZX2016000706)、宁波大学王宽诚幸福基金资助项目.

Progress in C—N Bonds Formation Using t-BuONO

Wei Wenting, Zhu Wenming, Wu Yi, Huang Yiling, Liang Hongze   

  1. School of Materials Science and Chemical Engineering, Ningbo University, Ningbo 315211
  • Received:2017-03-23 Revised:2017-04-18 Published:2017-05-10
  • Contact: 10.6023/cjoc201703039 E-mail:weiwenting@nbu.edu.cn
  • Supported by:

    Project supported by the Research Funds of Ningbo University (No. ZX2016000706) and the K. C. Wong Magna Fund in Ningbo University.

通过硝化反应构建C—N键是有机合成的一种重要策略.近年来,利用亚硝酸叔丁酯作为硝化试剂来合成含氮化合物引起化学家们的广泛关注,并取得了诸多的研究进展.该方法反应条件温和,反应区域选择性好,为C—N键构建提供了一种绿色、高效的途径.按反应底物类型的不同,对近年来亚硝酸叔丁酯参与C—N键构建的研究进展进行了综述.

关键词: 亚硝酸叔丁酯, C—N键, 硝化反应

The formation of C—N bonds by nitration is a powerful strategy for organic synthesis. Recently, the remarkable progress has been made in synthesis of nitrogen compounds using tert-butyl nitrite as nitration reagent. The present protocol, with a mild reaction condition and an excellent region selectivity, provides a green and efficient approach to construct C—N bonds. This review will summarize the recent development in this area on the basis of different substrates systems.

Key words: tert-butyl nitrite, C—N bond, nitration